Hs05504675_cn

• Gene Symbol: PPP1R1B
• Assay Reference Genome Location: Chr.17:39626361 on build GRCh38
• Cytoband: 17q12

Target Gene Details

• Entrez Gene ID: 84152
• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 1B
• Gene Aliases: DARPP-32, DARPP32
• Location: Chr.17:39626208-39636625 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R1B	XM_017025216.1	1	154	XP_016880705.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2047	Chr.17:39602374 - 39637631 on Build GRCh38	Insertion	NEUROD2 STARD3 PPP1R1B
nsv521294	Chr.17:39538456 - 39648605 on Build GRCh38	Loss	NEUROD2 STARD3 PPP1R1B CDK12
nsv516757	Chr.17:39625596 - 39678288 on Build GRCh38	Loss	STARD3 TCAP PGAP3 PNMT PPP1R1B
nsv574991	Chr.17:39613752 - 39674782 on Build GRCh38	Loss	STARD3 TCAP PGAP3 PNMT PPP1R1B
dgv40n68	Chr.17:39536627 - 39726611 on Build GRCh38	Loss	NEUROD2 STARD3 TCAP ERBB2 PGAP3 PNMT PPP1R1B MIR4728 CDK12

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase inhibitor

Gene Ontology Categories:

Process(es)

response to amphetamine
transcription, DNA-templated
signal transduction
negative regulation of female receptivity
visual learning
intracellular signal transduction
negative regulation of protein serine/threonine kinase activity

Function(s)

protein kinase inhibitor activity
cAMP-dependent protein kinase inhibitor activity
protein phosphatase inhibitor activity
protein serine/threonine phosphatase inhibitor activity
protein binding
protein phosphatase type 1 regulator activity
D1 dopamine receptor binding
D2 dopamine receptor binding
D3 dopamine receptor binding
D4 dopamine receptor binding
D5 dopamine receptor binding