Hs05558461_cn

• Gene Symbol: TAB1
• Assay Reference Genome Location: Chr.22:39408106 on build GRCh38
• Cytoband: 22q13.1

Target Gene Details

• Entrez Gene ID: 10454
• Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
• Gene Aliases: 3'-Tab1, MAP3K7IP1
• Location: Chr.22:39399754-39437127 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TAB1	NM_006116.2			NP_006107.1
	NM_153497.2			NP_705717.1
	AF425640.1			AAN32760.1
	AK291668.1
	AK296314.1
	AK308903.1
	AK312456.1
	AK316004.1
	BC050554.1			AAH50554.1
	U49928.1			AAC12660.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834199	Chr.22:39324389 - 39531343 on Build GRCh38	Loss	MGAT3-AS1 MIEF1 RPS19BP1 MGAT3 LOC100506472 ATF4 SYNGR1 TAB1
nsv834198	Chr.22:39222748 - 39409818 on Build GRCh38	Loss	SNORD43 PDGFB RPL3 SNORD139 SNORD83B SNORD83A SYNGR1 TAB1
esv3647764	Chr.22:39406723 - 39408566 on Build GRCh38	Loss	TAB1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

activation of MAPKKK activity
activation of MAPK activity
in utero embryonic development
stimulatory C-type lectin receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
heart morphogenesis
cardiac septum development
protein dephosphorylation
transforming growth factor beta receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
JNK cascade
lung development
aorta development
Fc-epsilon receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
coronary vasculature development
nucleotide-binding oligomerization domain containing signaling pathway

Function(s)

protein serine/threonine phosphatase activity
protein binding
enzyme activator activity
kinase activator activity