Hs05740832_cn

• Gene Symbol: EPHA8
• Assay Reference Genome Location: Chr.1:22563927 on build GRCh38
• Cytoband: 1p36.12

Target Gene Details

• Entrez Gene ID: 2046
• Gene Name: EPH receptor A8
• Gene Aliases: EEK, EK3, HEK3
• Location: Chr.1:22563508-22603594 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EPHA8	NM_001006943.1			NP_001006944.1
	XM_011540969.1			XP_011539271.1
	XM_011540970.1			XP_011539272.1
	XM_011540972.1			XP_011539274.1
	BC038796.1			AAH38796.1
	BC072417.1
	DR007053.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv184n54	Chr.1:22563554 - 22564322 on Build GRCh38	Loss	EPHA8
dgv182n54	Chr.1:22563356 - 22564473 on Build GRCh38	Gain	EPHA8
esv26050	Chr.1:22562682 - 22564686 on Build GRCh38	Gain	EPHA8
nsv545750	Chr.1:22559273 - 22564428 on Build GRCh38	Loss	EPHA8
dgv185n54	Chr.1:22563949 - 22564630 on Build GRCh38	Gain	EPHA8
nsv545753	Chr.1:22562979 - 22564162 on Build GRCh38	Loss	EPHA8
nsv509024	Chr.1:22536990 - 22581743 on Build GRCh38	Insertion	EPHA8
dgv187n54	Chr.1:22563965 - 22564649 on Build GRCh38	Loss	EPHA8
nsv545749	Chr.1:22551320 - 22625893 on Build GRCh38	Loss	EPHA8
dgv181n54	Chr.1:22562710 - 22564576 on Build GRCh38	Loss	EPHA8

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

substrate-dependent cell migration
cell adhesion
axon guidance
neuron remodeling
peptidyl-tyrosine phosphorylation
regulation of cell adhesion
neuron projection development
regulation of cell adhesion mediated by integrin
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
protein autophosphorylation
ephrin receptor signaling pathway

Function(s)

GPI-linked ephrin receptor activity
ATP binding