Hs05788655_cn

• Gene Symbol: PPP1R15B
• Assay Reference Genome Location: Chr.1:204401127 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 84919
• Gene Name: protein phosphatase 1 regulatory subunit 15B
• Gene Aliases: CREP, MSSGM2
• Location: Chr.1:204398684-204411880 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R15B	XM_005245551.4			XP_005245608.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952641	Chr.1:204396873 - 204410972 on Build GRCh38	Duplication	PPP1R15B
nsv522489	Chr.1:204396621 - 204401286 on Build GRCh38	Loss	PPP1R15B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
ER overload response
response to hydrogen peroxide
peptidyl-serine dephosphorylation
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Function(s)

protein serine/threonine phosphatase activity
protein binding