Hs05831726_cn

• Gene Symbol: EPHA4
• Assay Reference Genome Location: Chr.2:221418024 on build GRCh38
• Cytoband: 2q36.1

Target Gene Details

• Entrez Gene ID: 2043
• Gene Name: EPH receptor A4
• Gene Aliases: HEK8, SEK, TYRO1
• Location: Chr.2:221418027-221574202 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EPHA4	NM_001304536.1			NP_001291465.1
	NM_001304537.1			NP_001291466.1
	NM_004438.4			NP_004429.1
	XM_005246374.2			XP_005246431.1
	AK225181.1
	BM676153.1
	BM679073.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv584512	Chr.2:221255109 - 222040142 on Build GRCh38	Loss	EPHA4 LOC729770

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cell adhesion
adult walking behavior
motor neuron axon guidance
glial cell migration
peptidyl-tyrosine phosphorylation
corticospinal tract morphogenesis
regulation of GTPase activity
positive regulation of JUN kinase activity
protein autophosphorylation
ephrin receptor signaling pathway
negative regulation of axon regeneration
regulation of astrocyte differentiation
regulation of axonogenesis
positive regulation of dendrite morphogenesis
regulation of dendritic spine morphogenesis
nephric duct morphogenesis
fasciculation of sensory neuron axon
fasciculation of motor neuron axon
positive regulation of Rho guanyl-nucleotide exchange factor activity

Function(s)

protein kinase activity
GPI-linked ephrin receptor activity
transmembrane-ephrin receptor activity
protein binding
ATP binding
PH domain binding
identical protein binding
ephrin receptor binding
DH domain binding