Hs05991908_cn

• Gene Symbol: HBEGF
• Assay Reference Genome Location: Chr.5:140339807 on build GRCh38
• Cytoband: 5q31.3

Target Gene Details

• Entrez Gene ID: 1839
• Gene Name: heparin binding EGF like growth factor
• Gene Aliases: DTR, DTS, DTSF, HEGFL
• Location: Chr.5:140332843-140346603 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HBEGF	NM_001945.2			NP_001936.1
	AK222688.1			BAD96408.1
	AK307310.1
	AK313202.1
	BC033097.1			AAH33097.1
	M60278.1			AAA35956.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509090	Chr.5:140311306 - 140421024 on Build GRCh38	Insertion	ANKHD1-EIF4EBP3 SLC4A9 ANKHD1 HBEGF

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
signal transduction
epidermal growth factor receptor signaling pathway
muscle organ development
regulation of heart contraction
positive regulation of cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
positive regulation of cell migration
wound healing, spreading of epidermal cells
ERBB2 signaling pathway
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
negative regulation of elastin biosynthetic process
positive regulation of keratinocyte migration
positive regulation of protein kinase B signaling
cell chemotaxis
positive regulation of wound healing
regulation of cell motility

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
growth factor activity
heparin binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity