Hs06109333_cn

• Gene Symbol: LNPEP
• Assay Reference Genome Location: Chr.5:96937034 on build GRCh38
• Cytoband: 5q15

Target Gene Details

• Entrez Gene ID: 4012
• Gene Name: leucyl and cystinyl aminopeptidase
• Gene Aliases: CAP, IRAP, P-LAP, PLAP
• Location: Chr.5:96935642-97029411 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LNPEP	NM_005575.2			NP_005566.2
	AK096804.1	2	1343
	AK314226.1
	D50810.1			BAA09436.1
	U62768.1			AAB66672.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv598963	Chr.5:96749072 - 97027703 on Build GRCh38	Gain	CAST LNPEP ERAP2 LOC101929747 ERAP1
nsv598962	Chr.5:96722187 - 97557460 on Build GRCh38	Gain	LINC01340 LIX1 CAST LNPEP ERAP2 LOC101929747 RIOK2 ERAP1
nsv1021263	Chr.5:96060753 - 97448132 on Build GRCh38	Loss	LIX1 PCSK1 CAST MIR583 LNPEP ERAP2 LOC101929747 LOC101929710 RIOK2 ERAP1
nsv1028741	Chr.5:96746697 - 97036461 on Build GRCh38	Gain	CAST LNPEP ERAP2 LOC101929747 ERAP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

protein polyubiquitination
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
proteolysis
signal transduction
cell-cell signaling
female pregnancy
regulation of blood pressure
protein catabolic process
peptide catabolic process
SMAD protein signal transduction
membrane organization

Function(s)

aminopeptidase activity
protein binding
metallopeptidase activity
zinc ion binding
peptide binding
metalloaminopeptidase activity