Hs06308302_cn

• Gene Symbol: MAPK8IP1
• Assay Reference Genome Location: Chr.11:45892255 on build GRCh38
• Cytoband: 11p11.2

Target Gene Details

• Entrez Gene ID: 9479
• Gene Name: mitogen-activated protein kinase 8 interacting protein 1
• Gene Aliases: IB1, JIP-1, JIP1, PRKM8IP
• Location: Chr.11:45885496-45906465 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAPK8IP1	NM_005456.3			NP_005447.1
	AF074091.1			AAD20443.1
	BC068470.1			AAH68470.1
	BI548334.1
	DB473314.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv516442	Chr.11:45878411 - 45961834 on Build GRCh38	Loss	PEX16 MAPK8IP1 CRY2 LARGE2 C11orf94 PHF21A

More Information

Additional Information:

For this assay, SNP(s) [rs79798502] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
JUN phosphorylation
positive regulation of signal transduction
vesicle-mediated transport
negative regulation of JUN kinase activity
regulation of JNK cascade
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein kinase inhibitor activity
MAP-kinase scaffold activity
protein binding
JUN kinase binding
kinesin binding
mitogen-activated protein kinase kinase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding