Hs06321526_cn

• Gene Symbol: PRDX5
• Assay Reference Genome Location: Chr.11:64318526 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 25824
• Gene Name: peroxiredoxin 5
• Gene Aliases: ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V
• Location: Chr.11:64318088-64321823 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRDX5	NM_012094.4			NP_036226.1
	NM_181651.2			NP_857634.1
	NM_181652.2			NP_857635.1
	XM_005273882.4			XP_005273939.2
	AF110731.1			AAF03750.1
	AF112212.1			AAF17200.1
	AF124993.1			AAF27531.1
	AF197952.1			AAF04856.1
	AF231705.1			AAF78899.1
	AF242525.1			AAF99605.1
	BC110983.1			AAI10984.1
	BC113723.1
	BC113725.1
	BC143849.1
	BC171733.1
	BU598032.1
	CR457203.1			CAG33484.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3626659	Chr.11:64317918 - 64320057 on Build GRCh38	Loss	TRMT112 PRDX5
nsv951010	Chr.11:63942829 - 64352128 on Build GRCh38	Deletion	TRMT112 STIP1 LOC105369340 NUDT22 TEX40 NAA40 FLRT1 PRDX5 BAD TRPT1 DNAJC4 COX8A CCDC88B KCNK4 ESRRA FKBP2 VEGFB OTUB1 PLCB3 GPR137 FERMT3 MACROD1 PPP1R14B MIR7155 KCNK4-TEX40
dgv1963n54	Chr.11:64174262 - 64329761 on Build GRCh38	Loss	TRMT112 STIP1 LOC105369340 NUDT22 TEX40 FKBP2 VEGFB PRDX5 BAD TRPT1 DNAJC4 KCNK4 PLCB3 GPR137 FERMT3 PPP1R14B ESRRA KCNK4-TEX40
esv27107	Chr.11:64317946 - 64319938 on Build GRCh38	Loss	TRMT112 PRDX5
esv2667562	Chr.11:64317900 - 64320206 on Build GRCh38	Deletion	TRMT112 PRDX5
nsv832186	Chr.11:64204788 - 64402587 on Build GRCh38	Loss	TRMT112 RPS6KA4 MIR1237 LOC105369340 NUDT22 TEX40 FKBP2 VEGFB PRDX5 BAD TRPT1 DNAJC4 CCDC88B KCNK4 PLCB3 GPR137 FERMT3 PPP1R14B MIR7155 ESRRA KCNK4-TEX40

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
apoptotic process
inflammatory response
response to oxidative stress
negative regulation of transcription from RNA polymerase III promoter
cellular response to reactive oxygen species
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
cell redox homeostasis
oxidation-reduction process
cellular oxidant detoxification

Function(s)

RNA polymerase III regulatory region DNA binding
peroxidase activity
receptor binding
thioredoxin peroxidase activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
protein dimerization activity