Hs06447451_cn

• Gene Symbol: ADCYAP1
• Assay Reference Genome Location: Chr.18:906799 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 116
• Gene Name: adenylate cyclase activating polypeptide 1
• Gene Aliases: PACAP
• Location: Chr.18:904342-912172 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADCYAP1	NM_001099733.1			NP_001093203.1
	NM_001117.4			NP_001108.2
	XM_005258081.3			XP_005258138.1
	AB537500.1
	AK294233.1
	AK313050.1
	BC093837.1			AAH93837.1
	BC101803.1			AAI01804.1
	DA145895.1
	DC320719.1
	DN991692.1
	S83513.1			AAB21470.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517252	Chr.18:902327 - 910634 on Build GRCh38	Loss	ADCYAP1
dgv5810n54	Chr.18:351004 - 2238246 on Build GRCh38	Gain	LINC00470 ENOSF1 CLUL1 YES1 ADCYAP1 LOC388456 TYMS CETN1 LOC105376854 TYMSOS COLEC12
nsv528169	Chr.18:551688 - 2240220 on Build GRCh38	Loss	LINC00470 ENOSF1 CLUL1 YES1 ADCYAP1 LOC388456 TYMS CETN1 TYMSOS
dgv5811n54	Chr.18:841320 - 1798153 on Build GRCh38	Gain	LINC00470 ADCYAP1 LOC388456
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	NDC80 METTL4 SMCHD1 MIR8078 LOC388456 TYMS TYMSOS COLEC12 LINC00470 ENOSF1 CLUL1 ROCK1P1 EMILIN2 YES1 THOC1 ADCYAP1 CBX3P2 LOC101926997 CETN1 LOC105376854 USP14
nsv518677	Chr.18:895554 - 907709 on Build GRCh38	Loss	ADCYAP1
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	MIR8078 LOC388456 TYMS TYMSOS COLEC12 LINC00470 ENOSF1 CLUL1 ROCK1P1 YES1 THOC1 ADCYAP1 CETN1 LOC105376854 USP14

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

neuropeptide

Gene Ontology Categories:

Process(es)

ovarian follicle development
behavioral fear response
histamine secretion
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to non-antigenic stimulus
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
female pregnancy
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
negative regulation of muscle cell apoptotic process
positive regulation of neuron projection development
sensory perception of pain
cAMP-mediated signaling
pituitary gland development
neuron projection development
positive regulation of interleukin-6 production
regulation of protein localization
negative regulation of GTPase activity
response to starvation
negative regulation of potassium ion transport
positive regulation of GTPase activity
response to ethanol
negative regulation of cell cycle
positive regulation of protein kinase activity
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
ATP metabolic process
positive regulation of synaptic transmission, glutamatergic
regulation of postsynaptic membrane potential
positive regulation of growth hormone secretion
negative regulation of glial cell proliferation
positive regulation of ERK1 and ERK2 cascade
regulation of oligodendrocyte progenitor proliferation
cellular response to glucocorticoid stimulus
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of somatostatin secretion

Function(s)

receptor signaling protein activity
receptor binding
neuropeptide hormone activity
protein binding
pituitary adenylate cyclase activating polypeptide activity
pituitary adenylate cyclase-activating polypeptide receptor binding
peptide hormone receptor binding