Hs06477998_cn

• Gene Symbol: YES1
• Assay Reference Genome Location: Chr.18:738238 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 7525
• Gene Name: YES proto-oncogene 1, Src family tyrosine kinase
• Gene Aliases: HsT441, P61-YES, Yes, c-yes
• Location: Chr.18:721592-812326 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YES1	NM_005433.3			NP_005424.1
	XM_005258139.3			XP_005258196.1
	XM_017025960.1			XP_016881449.1
	AK314063.1
	BC048960.1			AAH48960.1
	M15990.1			AAA35735.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv576236	Chr.18:319176 - 794272 on Build GRCh38	Gain	TYMSOS CETN1 LOC105376854 CLUL1 YES1 COLEC12 TYMS ENOSF1
dgv5810n54	Chr.18:351004 - 2238246 on Build GRCh38	Gain	TYMSOS CETN1 LOC105376854 ADCYAP1 LOC388456 CLUL1 YES1 COLEC12 TYMS LINC00470 ENOSF1
nsv576242	Chr.18:567127 - 841320 on Build GRCh38	Gain	TYMSOS CETN1 CLUL1 YES1 TYMS ENOSF1
esv3641497	Chr.18:551569 - 745897 on Build GRCh38	Gain	TYMSOS CETN1 CLUL1 YES1 TYMS ENOSF1
nsv528169	Chr.18:551688 - 2240220 on Build GRCh38	Loss	TYMSOS CETN1 ADCYAP1 LOC388456 CLUL1 YES1 TYMS LINC00470 ENOSF1
nsv1060188	Chr.18:575087 - 863351 on Build GRCh38	Gain	TYMSOS CETN1 CLUL1 YES1 TYMS ENOSF1
esv2761984	Chr.18:724222 - 855263 on Build GRCh38	Loss	YES1
esv3893055	Chr.18:415105 - 743226 on Build GRCh38	Gain	TYMSOS CETN1 LOC105376854 CLUL1 YES1 COLEC12 TYMS ENOSF1
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	TYMSOS THOC1 CBX3P2 USP14 LOC105376854 CLUL1 YES1 METTL4 LINC00470 SMCHD1 ENOSF1 MIR8078 LOC101926997 CETN1 NDC80 EMILIN2 ADCYAP1 ROCK1P1 LOC388456 COLEC12 TYMS
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	TYMSOS THOC1 USP14 LOC105376854 CLUL1 YES1 LINC00470 ENOSF1 MIR8078 CETN1 ADCYAP1 ROCK1P1 LOC388456 COLEC12 TYMS

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cellular protein modification process
transmembrane receptor protein tyrosine kinase signaling pathway
glucose transport
cell differentiation
T cell costimulation
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of cell proliferation
regulation of vascular permeability
innate immune response
positive regulation of transcription from RNA polymerase II promoter
ephrin receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte migration
cellular response to retinoic acid
cellular response to transforming growth factor beta stimulus

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
epidermal growth factor receptor binding
protein binding
ATP binding
enzyme binding
ion channel binding