Hs06496619_cn

• Gene Symbol: LDLRAD4
• Assay Reference Genome Location: Chr.18:13218454 on build GRCh38
• Cytoband: 18p11.21

Target Gene Details

• Entrez Gene ID: 753
• Gene Name: low density lipoprotein receptor class A domain containing 4
• Gene Aliases: C18orf1
• Location: Chr.18:13217691-13652754 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LDLRAD4	XM_017025963.1			XP_016881452.1
	XM_017025964.1			XP_016881453.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833591	Chr.18:13093778 - 13253749 on Build GRCh38	Gain	CEP192 LDLRAD4
nsv828183	Chr.18:13211475 - 13222377 on Build GRCh38	Gain	LDLRAD4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of epithelial to mesenchymal transition
negative regulation of SMAD protein complex assembly
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of pathway-restricted SMAD protein phosphorylation

Function(s)

R-SMAD binding