Hs06507416_cn

• Gene Symbol: YES1
• Assay Reference Genome Location: Chr.18:730625 on build GRCh38
• Cytoband: 18p11.32

Target Gene Details

• Entrez Gene ID: 7525
• Gene Name: YES proto-oncogene 1, Src family tyrosine kinase
• Gene Aliases: HsT441, P61-YES, Yes, c-yes
• Location: Chr.18:721592-812326 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YES1	NM_005433.3			NP_005424.1
	XM_005258139.3			XP_005258196.1
	XM_017025960.1			XP_016881449.1
	AK314063.1
	BC048960.1			AAH48960.1
	M15990.1			AAA35735.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv576236	Chr.18:319176 - 794272 on Build GRCh38	Gain	TYMSOS YES1 TYMS CLUL1 ENOSF1 CETN1 LOC105376854 COLEC12
dgv5810n54	Chr.18:351004 - 2238246 on Build GRCh38	Gain	TYMSOS YES1 LINC00470 LOC388456 TYMS CLUL1 ADCYAP1 ENOSF1 CETN1 LOC105376854 COLEC12
nsv576242	Chr.18:567127 - 841320 on Build GRCh38	Gain	TYMSOS YES1 TYMS CLUL1 ENOSF1 CETN1
esv3641497	Chr.18:551569 - 745897 on Build GRCh38	Gain	TYMSOS YES1 TYMS CLUL1 ENOSF1 CETN1
nsv528169	Chr.18:551688 - 2240220 on Build GRCh38	Loss	TYMSOS YES1 LINC00470 LOC388456 TYMS CLUL1 ADCYAP1 ENOSF1 CETN1
nsv1060188	Chr.18:575087 - 863351 on Build GRCh38	Gain	TYMSOS YES1 TYMS CLUL1 ENOSF1 CETN1
esv2761984	Chr.18:724222 - 855263 on Build GRCh38	Loss	YES1
esv3893055	Chr.18:415105 - 743226 on Build GRCh38	Gain	TYMSOS YES1 TYMS CLUL1 ENOSF1 CETN1 LOC105376854 COLEC12
nsv482935	Chr.18:10001 - 2900002 on Build GRCh38	Loss	TYMSOS THOC1 YES1 EMILIN2 LINC00470 TYMS SMCHD1 LOC101926997 NDC80 COLEC12 USP14 METTL4 LOC388456 CLUL1 ADCYAP1 ENOSF1 CETN1 LOC105376854 MIR8078 CBX3P2 ROCK1P1
nsv576228	Chr.18:69836 - 1506323 on Build GRCh38	Loss	TYMSOS THOC1 YES1 LINC00470 TYMS COLEC12 USP14 LOC388456 CLUL1 ADCYAP1 ENOSF1 CETN1 LOC105376854 MIR8078 ROCK1P1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cellular protein modification process
transmembrane receptor protein tyrosine kinase signaling pathway
glucose transport
cell differentiation
T cell costimulation
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of cell proliferation
regulation of vascular permeability
innate immune response
positive regulation of transcription from RNA polymerase II promoter
ephrin receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte migration
cellular response to retinoic acid
cellular response to transforming growth factor beta stimulus

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
epidermal growth factor receptor binding
protein binding
ATP binding
enzyme binding
ion channel binding