Hs06513612_cn

• Gene Symbol: EPHB2
• Assay Reference Genome Location: Chr.1:22734823 on build GRCh38
• Cytoband: 1p36.12

Target Gene Details

• Entrez Gene ID: 2048
• Gene Name: EPH receptor B2
• Gene Aliases: CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5
• Location: Chr.1:22710770-22921500 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EPHB2	NM_001309192.1			NP_001296121.1
	NM_001309193.1			NP_001296122.1
	NM_004442.7			NP_004433.2
	NM_017449.4			NP_059145.2
	XM_006710442.3			XP_006710505.1
	AB210018.1
	AF025304.1			AAB94602.1
	AK299701.1
	BC067861.1			AAH67861.1
	DB282024.1
	L36643.1			AAA74244.1
	L41939.1			AAA99310.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34161	Chr.1:22599762 - 22817730 on Build GRCh38	Loss	EPHA8 C1QB C1QC EPHB2 MIR6127 MIR4684 C1QA

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
urogenital system development
nervous system development
axon guidance
axonal fasciculation
learning
phosphorylation
peptidyl-tyrosine phosphorylation
optic nerve morphogenesis
central nervous system projection neuron axonogenesis
corpus callosum development
retinal ganglion cell axon guidance
inner ear morphogenesis
ephrin receptor signaling pathway
positive regulation of long-term neuronal synaptic plasticity
camera-type eye morphogenesis
negative regulation of axonogenesis
regulation of body fluid levels
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
commissural neuron axon guidance

Function(s)

protein tyrosine kinase activity
transmembrane-ephrin receptor activity
receptor binding
protein binding
ATP binding
axon guidance receptor activity
identical protein binding