Hs06611780_cn

• Gene Symbol: MST1R
• Assay Reference Genome Location: Chr.3:49886592 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 4486
• Gene Name: macrophage stimulating 1 receptor
• Gene Aliases: CD136, CDw136, PTK8, RON
• Location: Chr.3:49886471-49903637 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MST1R	XM_011533743.2	18	4641	XP_011532045.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834688	Chr.3:49773682 - 49981866 on Build GRCh38	Loss	MST1R CDHR4 UBA7 MIR5193 FAM212A MON1A TRAIP IP6K1 RBM6 CAMKV
dgv890e214	Chr.3:49882736 - 49888371 on Build GRCh38	Loss	MST1R
esv3596133	Chr.3:49882993 - 49887598 on Build GRCh38	Gain	MST1R

More Information

Additional Information:

For this assay, SNP(s) [rs73834118] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

movement of cell or subcellular component
defense response
signal transduction
single fertilization
positive regulation of cell proliferation
response to virus
peptidyl-tyrosine phosphorylation
macrophage colony-stimulating factor signaling pathway
positive regulation of MAP kinase activity
innate immune response
hepatocyte growth factor receptor signaling pathway
positive regulation of protein kinase B signaling

Function(s)

macrophage colony-stimulating factor receptor activity
protein binding
ATP binding
enzyme binding