Hs06621706_cn

• Gene Symbol: TOPBP1
• Assay Reference Genome Location: Chr.3:133602081 on build GRCh38
• Cytoband: 3q22.1

Target Gene Details

• Entrez Gene ID: 11073
• Gene Name: topoisomerase (DNA) II binding protein 1
• Gene Aliases: TOP2BP1
• Location: Chr.3:133600605-133662380 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOPBP1	NM_007027.3			NP_008958.2
	XM_005247076.3			XP_005247133.1
	XM_017005636.1			XP_016861125.1
	XM_017005637.1			XP_016861126.1
	AB019397.1			BAA34202.1
	AK026229.1
	AK302584.1
	BC126209.1
	BC151237.1
	D87448.1

More Information

Additional Information:

For this assay, SNP(s) [rs114946023] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

DNA metabolic process
DNA replication
DNA repair
cellular response to DNA damage stimulus
response to ionizing radiation
regulation of signal transduction by p53 class mediator

Function(s)

DNA binding
protein binding
protein C-terminus binding
identical protein binding