Hs06744553_cn

• Gene Symbol: FRK
• Assay Reference Genome Location: Chr.6:115970042 on build GRCh38
• Cytoband: 6q22.1

Target Gene Details

• Entrez Gene ID: 2444
• Gene Name: fyn related Src family tyrosine kinase
• Gene Aliases: GTK, PTK5, RAK
• Location: Chr.6:115941031-116100739 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FRK	NM_002031.2			NP_002022.1
	XM_005266880.4			XP_005266937.1
	XM_005266881.2			XP_005266938.1
	XM_005266882.4			XP_005266939.1
	XM_011535653.2			XP_011533955.1
	XM_011535654.2			XP_011533956.1
	XM_011535655.2			XP_011533957.1
	XM_011535656.2			XP_011533958.1
	XM_017010645.1			XP_016866134.1
	AK302264.1
	AK313314.1
	BC012916.1			AAH12916.1
	U00803.1			AAA18284.1
	U22322.1			AAC50116.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1029998	Chr.6:115763322 - 116057888 on Build GRCh38	Loss	FRK TPI1P3
nsv523972	Chr.6:115958024 - 116809541 on Build GRCh38	Gain	FAM26F FAM26E RSPH4A FAM26D FRK GPRC6A LOC100287467 FAM162B ZUFSP NT5DC1 DSE COL10A1 TSPYL1 KPNA5 TRAPPC3L RWDD1 TPI1P3 TSPYL4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
negative regulation of cell proliferation
cell differentiation
peptidyl-tyrosine autophosphorylation
innate immune response

Function(s)

non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding