Hs06781401_cn

• Gene Symbol: MYLIP
• Assay Reference Genome Location: Chr.6:16129076 on build GRCh38
• Cytoband: 6p22.3

Target Gene Details

• Entrez Gene ID: 29116
• Gene Name: myosin regulatory light chain interacting protein
• Gene Aliases: IDOL, MIR
• Location: Chr.6:16129086-16151015 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MYLIP	NM_013262.3			NP_037394.2
	XM_005249032.2			XP_005249089.1
	XM_017010789.1			XP_016866278.1
	AF258586.1			AAG23789.1
	AK074391.1
	AK314648.1
	BC002860.2			AAH02860.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv950132	Chr.6:16128770 - 16148769 on Build GRCh38	Duplication	MIR4639 MYLIP
nsv5209	Chr.6:16117893 - 16151799 on Build GRCh38	Insertion	MIR4639 MYLIP

More Information

Additional Information:

For this assay, SNP(s) [rs182730226] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein polyubiquitination
movement of cell or subcellular component
nervous system development
negative regulation of low-density lipoprotein particle clearance
protein ubiquitination
protein destabilization
regulation of low-density lipoprotein particle receptor catabolic process
cholesterol homeostasis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process

Function(s)

ubiquitin-protein transferase activity
protein binding
cytoskeletal protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase activity