Hs06802731_cn

• Gene Symbol: APOM
• Assay Reference Genome Location: Chr.6:31652898 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 55937
• Gene Name: apolipoprotein M
• Gene Aliases: G3a, HSPC336, NG20, apo-M
• Location: Chr.6:31652410-31658210 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOM	NM_001256169.1			NP_001243098.1
	NR_045828.1
	AA846749.1
	AF161454.1			AAF29014.1
	BF344944.1
	CB054016.1
	CN428415.1

Target Gene Details

• Entrez Gene ID: 7917
• Gene Name: BCL2 associated athanogene 6
• Gene Aliases: BAG-6, BAT3, D6S52E, G3
• Location: Chr.6:31639028-31660900 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BAG6	XM_011514892.2	1	786	XP_011513194.1
	XM_017011275.1	1	786	XP_016866764.1
	XM_017011279.1			XP_016866768.1
	XM_017011283.1	1	786	XP_016866772.1
	XM_017011284.1	1	786	XP_016866773.1
	XM_017011287.1	1	786	XP_016866776.1
	XM_017011289.1	1	786	XP_016866778.1
	XM_017011290.1	1	786	XP_016866779.1
	XM_017011291.1	1	786	XP_016866780.1
	XM_017011292.1	1	786	XP_016866781.1
	XM_017011294.1	1	786	XP_016866783.1
	XM_017011295.1	1	786	XP_016866784.1
	XM_017011296.1	1	786	XP_016866785.1
	XM_017011298.1	1	786	XP_016866787.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	MIR6832 LOC102725068 TNF ABHD16A AIF1 HLA-DRB6 LSM2 LY6G6C EGFL8 MIR6721 CLIC1 NEU1 C6orf25 TNXA MICB LTB SNORD117 MSH5-SAPCD1 LY6G5B C4B SNORD84 HCG23 C2 STK19 NELFE NCR3 LY6G5C LY6G6F LOC101929163 HCP5 ZBTB12 BTNL2 NOTCH4 C6orf48 HSPA1L SNORA38 LY6G6E VARS MIR1236 C4A HSPA1A TNXB CFB HLA-DRA FKBPL PPT2-EGFL8 DDX39B-AS1 SAPCD1-AS1 PRRT1 PRRC2A HLA-DRB5 HSPA1B PPT2 MCCD1 AGPAT1 GPSM3 PBX2 C6orf47 CSNK2B LST1 HCG26 BAG6 NFKBIL1 SKIV2L GPANK1 C2-AS1 LOC100287329 MIR4646 SAPCD1 MSH5 C6orf10 DDAH2 SNORD48 LOC100507547 SLC44A4 VWA7 RNF5 EHMT2 DDX39B LY6G6D ATP6V1G2 ATF6B APOM CYP21A1P ATP6V1G2-DDX39B DXO AGER CYP21A2 LTA SNORD52 HLA-DRB1 MIR6833
nsv601942	Chr.6:31607499 - 31664357 on Build GRCh38	Loss	GPANK1 MIR6832 AIF1 C6orf47 APOM SNORA38 PRRC2A BAG6
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	MIR6832 LOC102725068 TNF ABHD16A AIF1 LSM2 LY6G6C MIR6891 CLIC1 NEU1 C6orf25 TNXA MICB LTB SNORD117 MSH5-SAPCD1 LY6G5B C4B SNORD84 C2 STK19 NELFE NCR3 LY6G5C LY6G6F HCP5 ZBTB12 C6orf48 HSPA1L SNORA38 LY6G6E VARS MIR1236 C4A HSPA1A TNXB CFB DDX39B-AS1 SAPCD1-AS1 MICA PRRC2A HSPA1B MCCD1 C6orf47 CSNK2B LST1 HCG26 BAG6 NFKBIL1 SKIV2L GPANK1 C2-AS1 LOC100287329 MIR4646 SAPCD1 MSH5 DDAH2 SNORD48 SLC44A4 VWA7 EHMT2 DDX39B LY6G6D ATP6V1G2 APOM CYP21A1P ATP6V1G2-DDX39B DXO HLA-B CYP21A2 LTA SNORD52
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	MIR6832 LOC102725068 CLIC1 NEU1 C6orf25 TNXA B3GALT4 LTB DAXX SLC39A7 LY6G5B HLA-DQA2 C4B TAP2 SNORD84 C2 PSMB8-AS1 NELFE LY6G6F LOC101929163 HLA-DOA HCP5 ZBTB12 BTNL2 NOTCH4 HSPA1L ZBTB9 HLA-DQB2 PSMB9 RXRB SNORA38 HLA-DPA1 CUTA LY6G6E TAP1 VARS PFDN6 MIR1236 HSPA1A TNXB CFB HLA-DRA SAPCD1-AS1 PRRT1 PRRC2A HSPA1B MCCD1 AGPAT1 GPSM3 PBX2 C6orf47 CSNK2B LST1 HLA-DPB1 NFKBIL1 PHF1 GPANK1 LOC100287329 ZBTB22 HLA-DQB1-AS1 SAPCD1 MSH5 TAPBP SYNGAP1 C6orf10 SNORD48 MIR219A1 LOC100507547 SLC44A4 RGL2 APOM HCG25 LTA MIR6834 HLA-DRB1 PPP1R2P1 TNF ABHD16A AIF1 HLA-DRB6 LSM2 LY6G6C HLA-DOB VPS52 EGFL8 MIR6721 HLA-DMB MICB HCG24 SNORD117 HSD17B8 MSH5-SAPCD1 HLA-DPB2 COL11A2 HCG23 STK19 NCR3 LY6G5C C6orf48 BRD2 RPS18 PSMB8 C4A FKBPL HLA-DQA1 PPT2-EGFL8 DDX39B-AS1 MIR6873 HLA-DRB5 KIFC1 PPT2 RING1 HCG26 BAG6 SKIV2L C2-AS1 LOC100294145 MIR4646 HLA-DQB1 DDAH2 VWA7 HLA-DMA RNF5 EHMT2 DDX39B WDR46 LY6G6D MIR3135B ATP6V1G2 MIR5004 ATF6B CYP21A1P ATP6V1G2-DDX39B DXO AGER CYP21A2 SNORD52 MIR6833
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	MIR6832 LOC102725068 CLIC1 NEU1 C6orf25 TNXA B3GALT4 LTB DAXX SLC39A7 LY6G5B HLA-DQA2 C4B TAP2 SNORD84 C2 PSMB8-AS1 NELFE LY6G6F LOC101929163 HLA-DOA HCP5 ZBTB12 BTNL2 NOTCH4 HSPA1L ZBTB9 HLA-DQB2 PSMB9 RXRB SNORA38 HLA-DPA1 CUTA LY6G6E TAP1 VARS PFDN6 MIR1236 HSPA1A TNXB CFB HLA-DRA SAPCD1-AS1 PRRT1 PRRC2A HSPA1B MCCD1 AGPAT1 GPSM3 PBX2 C6orf47 CSNK2B LST1 HLA-DPB1 NFKBIL1 PHF1 GPANK1 LOC100287329 ZBTB22 HLA-DQB1-AS1 SAPCD1 MSH5 TAPBP SYNGAP1 C6orf10 SNORD48 MIR219A1 LOC100507547 SLC44A4 RGL2 APOM HCG25 LTA MIR6834 HLA-DRB1 PPP1R2P1 TNF ABHD16A AIF1 HLA-DRB6 LSM2 LY6G6C HLA-DOB VPS52 EGFL8 MIR6721 HLA-DMB MICB HCG24 SNORD117 HSD17B8 MSH5-SAPCD1 HLA-DPB2 COL11A2 HCG23 STK19 NCR3 LY6G5C C6orf48 BRD2 RPS18 PSMB8 C4A FKBPL HLA-DQA1 PPT2-EGFL8 DDX39B-AS1 MIR6873 HLA-DRB5 KIFC1 PPT2 RING1 HCG26 BAG6 SKIV2L C2-AS1 LOC100294145 MIR4646 HLA-DQB1 DDAH2 VWA7 HLA-DMA RNF5 EHMT2 DDX39B WDR46 LY6G6D MIR3135B ATP6V1G2 MIR5004 ATF6B CYP21A1P ATP6V1G2-DDX39B DXO AGER CYP21A2 SNORD52 MIR6833
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	MIR6832 LOC102725068 TNF ABHD16A AIF1 LSM2 LY6G6C EGFL8 MIR6891 MIR6721 CLIC1 NEU1 C6orf25 TNXA MICB LTB SNORD117 MSH5-SAPCD1 LY6G5B C4B SNORD84 HCG23 C2 STK19 NELFE NCR3 LY6G5C LY6G6F LOC101929163 HCP5 ZBTB12 BTNL2 NOTCH4 C6orf48 HSPA1L SNORA38 LY6G6E VARS MIR1236 C4A HSPA1A TNXB CFB HLA-DRA FKBPL PPT2-EGFL8 DDX39B-AS1 SAPCD1-AS1 PRRT1 MICA PRRC2A HSPA1B PPT2 MCCD1 AGPAT1 GPSM3 PBX2 C6orf47 CSNK2B LST1 HCG26 BAG6 NFKBIL1 SKIV2L GPANK1 C2-AS1 LOC100287329 MIR4646 SAPCD1 MSH5 C6orf10 DDAH2 SNORD48 LOC100507547 SLC44A4 VWA7 RNF5 EHMT2 DDX39B LY6G6D ATP6V1G2 ATF6B APOM CYP21A1P ATP6V1G2-DDX39B DXO HLA-B AGER CYP21A2 LTA SNORD52 MIR6833
nsv1161370	Chr.6:31600692 - 31714252 on Build GRCh38	Deletion	LY6G6F MIR6832 ABHD16A AIF1 C6orf47 CSNK2B APOM SNORA38 BAG6 GPANK1 LY6G6E MIR4646 LY6G5B PRRC2A LY6G5C
nsv830627	Chr.6:31528437 - 31692173 on Build GRCh38	Loss	MIR6832 TNF ABHD16A AIF1 MCCD1 C6orf47 CSNK2B LST1 LTB BAG6 NFKBIL1 GPANK1 SNORD117 LOC100287329 LY6G5B SNORD84 NCR3 LY6G5C DDX39B ATP6V1G2 APOM SNORA38 ATP6V1G2-DDX39B LTA DDX39B-AS1 PRRC2A

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

apolipoprotein, transfer/carrier protein, chaperone

Gene Ontology Categories:

Process(es)

retinoid metabolic process
response to glucose
cholesterol efflux
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
negative regulation of plasma lipoprotein particle oxidation
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
cellular oxidant detoxification
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway

Function(s)

lipid transporter activity
phospholipid binding
antioxidant activity
protein binding
Hsp70 protein binding
polyubiquitin binding
ubiquitin protein ligase binding
ribosome binding
misfolded protein binding
proteasome binding
ubiquitin-specific protease binding