Hs06802731_cn

• Gene Symbol: APOM
• Assay Reference Genome Location: Chr.6:31652898 on build GRCh38
• Cytoband: 6p21.33

Target Gene Details

• Entrez Gene ID: 55937
• Gene Name: apolipoprotein M
• Gene Aliases: G3a, HSPC336, NG20, apo-M
• Location: Chr.6:31652410-31658210 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOM	NM_001256169.1			NP_001243098.1
	NR_045828.1
	AA846749.1
	AF161454.1			AAF29014.1
	BF344944.1
	CB054016.1
	CN428415.1

Target Gene Details

• Entrez Gene ID: 7917
• Gene Name: BCL2 associated athanogene 6
• Gene Aliases: BAG-6, BAT3, D6S52E, G3
• Location: Chr.6:31639028-31660900 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BAG6	XM_011514892.2	1	786	XP_011513194.1
	XM_017011275.1	1	786	XP_016866764.1
	XM_017011279.1			XP_016866768.1
	XM_017011283.1	1	786	XP_016866772.1
	XM_017011284.1	1	786	XP_016866773.1
	XM_017011287.1	1	786	XP_016866776.1
	XM_017011289.1	1	786	XP_016866778.1
	XM_017011290.1	1	786	XP_016866779.1
	XM_017011291.1	1	786	XP_016866780.1
	XM_017011292.1	1	786	XP_016866781.1
	XM_017011294.1	1	786	XP_016866783.1
	XM_017011295.1	1	786	XP_016866784.1
	XM_017011296.1	1	786	XP_016866785.1
	XM_017011298.1	1	786	XP_016866787.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv462871	Chr.6:31607499 - 31664357 on Build GRCh38	Loss	MIR6832 PRRC2A AIF1 SNORA38 C6orf47 GPANK1 APOM BAG6
nsv1126749	Chr.6:31457323 - 32594423 on Build GRCh38	Deletion	MIR4646 SAPCD1-AS1 MIR6721 APOM HSPA1B LY6G6F SLC44A4 SKIV2L LST1 ATF6B LY6G5C PRRC2A VARS LY6G6C HLA-DRA NCR3 MIR1236 LY6G6E BTNL2 C6orf25 BAG6 TNXB DXO PPT2 MICB AGER EGFL8 SAPCD1 CYP21A1P C2-AS1 FKBPL CFB ATP6V1G2 PBX2 HLA-DRB6 HSPA1L MIR6833 SNORA38 GPANK1 GPSM3 LY6G6D HLA-DRB5 LOC100507547 RNF5 HSPA1A MSH5 MIR6832 SNORD117 CLIC1 C4A LOC102725068 DDX39B HLA-DRB1 LOC101929163 LY6G5B ATP6V1G2-DDX39B C6orf48 STK19 TNXA VWA7 NOTCH4 NFKBIL1 SNORD84 C2 DDX39B-AS1 SNORD52 AGPAT1 TNF MCCD1 LTA ZBTB12 MSH5-SAPCD1 HCG23 LSM2 LTB PPT2-EGFL8 SNORD48 LOC100287329 PRRT1 NELFE CYP21A2 DDAH2 ABHD16A HCG26 AIF1 C4B C6orf47 C6orf10 HCP5 EHMT2 CSNK2B NEU1
nsv1073969	Chr.6:31456422 - 33480523 on Build GRCh38	Deletion	SAPCD1-AS1 HLA-DPB1 CUTA LY6G6F SKIV2L PRRC2A VARS PHF1 LY6G6C SYNGAP1 NCR3 MIR1236 RGL2 HLA-DQA1 LY6G6E C6orf25 BAG6 HLA-DQB1-AS1 PPT2 MIR219A1 EGFL8 SAPCD1 HSD17B8 CYP21A1P SLC39A7 PSMB9 C2-AS1 ATP6V1G2 PBX2 HSPA1L HLA-DPB2 MIR6833 SNORA38 LY6G6D LOC100507547 RNF5 SNORD117 LOC102725068 HCG24 ATP6V1G2-DDX39B TNXA TAP1 NOTCH4 SNORD84 C2 DDX39B-AS1 HLA-DQA2 TAP2 MCCD1 LTA LSM2 LTB PPT2-EGFL8 PRRT1 NELFE CYP21A2 ABHD16A AIF1 C4B C6orf47 C6orf10 EHMT2 HLA-DOA MIR4646 PPP1R2P1 PSMB8-AS1 MIR6721 APOM HSPA1B HLA-DQB2 SLC44A4 LST1 ATF6B MIR6873 LY6G5C HLA-DRA TAPBP BTNL2 TNXB DXO ZBTB9 MICB MIR3135B BRD2 AGER HLA-DMA FKBPL LOC100294145 CFB HCG25 HLA-DRB6 RPS18 MIR6834 PSMB8 RXRB GPANK1 GPSM3 HLA-DRB5 HSPA1A MSH5 HLA-DQB1 MIR6832 CLIC1 C4A DDX39B HLA-DRB1 LOC101929163 LY6G5B C6orf48 MIR5004 STK19 VWA7 NFKBIL1 ZBTB22 HLA-DOB SNORD52 KIFC1 AGPAT1 TNF HLA-DPA1 ZBTB12 MSH5-SAPCD1 HCG23 SNORD48 LOC100287329 VPS52 PFDN6 DDAH2 B3GALT4 HCG26 RING1 HCP5 COL11A2 CSNK2B WDR46 HLA-DMB NEU1 DAXX
dgv10403n54	Chr.6:31312324 - 32049763 on Build GRCh38	Loss	MIR4646 SAPCD1-AS1 APOM HSPA1B MICA LY6G6F SLC44A4 SKIV2L LST1 HLA-B LY6G5C PRRC2A VARS LY6G6C NCR3 MIR1236 LY6G6E C6orf25 BAG6 TNXB DXO MICB MIR6891 SAPCD1 CYP21A1P C2-AS1 CFB ATP6V1G2 HSPA1L SNORA38 GPANK1 LY6G6D HSPA1A MSH5 MIR6832 SNORD117 CLIC1 C4A LOC102725068 DDX39B LY6G5B ATP6V1G2-DDX39B C6orf48 STK19 TNXA VWA7 NFKBIL1 SNORD84 C2 DDX39B-AS1 SNORD52 TNF MCCD1 LTA ZBTB12 MSH5-SAPCD1 LSM2 LTB SNORD48 LOC100287329 NELFE CYP21A2 DDAH2 ABHD16A HCG26 AIF1 C4B C6orf47 HCP5 EHMT2 CSNK2B NEU1
nsv1112900	Chr.6:31455323 - 33480423 on Build GRCh38	Deletion	SAPCD1-AS1 HLA-DPB1 CUTA LY6G6F SKIV2L PRRC2A VARS PHF1 LY6G6C SYNGAP1 NCR3 MIR1236 RGL2 HLA-DQA1 LY6G6E C6orf25 BAG6 HLA-DQB1-AS1 PPT2 MIR219A1 EGFL8 SAPCD1 HSD17B8 CYP21A1P SLC39A7 PSMB9 C2-AS1 ATP6V1G2 PBX2 HSPA1L HLA-DPB2 MIR6833 SNORA38 LY6G6D LOC100507547 RNF5 SNORD117 LOC102725068 HCG24 ATP6V1G2-DDX39B TNXA TAP1 NOTCH4 SNORD84 C2 DDX39B-AS1 HLA-DQA2 TAP2 MCCD1 LTA LSM2 LTB PPT2-EGFL8 PRRT1 NELFE CYP21A2 ABHD16A AIF1 C4B C6orf47 C6orf10 EHMT2 HLA-DOA MIR4646 PPP1R2P1 PSMB8-AS1 MIR6721 APOM HSPA1B HLA-DQB2 SLC44A4 LST1 ATF6B MIR6873 LY6G5C HLA-DRA TAPBP BTNL2 TNXB DXO ZBTB9 MICB MIR3135B BRD2 AGER HLA-DMA FKBPL LOC100294145 CFB HCG25 HLA-DRB6 RPS18 MIR6834 PSMB8 RXRB GPANK1 GPSM3 HLA-DRB5 HSPA1A MSH5 HLA-DQB1 MIR6832 CLIC1 C4A DDX39B HLA-DRB1 LOC101929163 LY6G5B C6orf48 MIR5004 STK19 VWA7 NFKBIL1 ZBTB22 HLA-DOB SNORD52 KIFC1 AGPAT1 TNF HLA-DPA1 ZBTB12 MSH5-SAPCD1 HCG23 SNORD48 LOC100287329 VPS52 PFDN6 DDAH2 B3GALT4 HCG26 RING1 HCP5 COL11A2 CSNK2B WDR46 HLA-DMB NEU1 DAXX
dgv10404n54	Chr.6:31312550 - 32516591 on Build GRCh38	Loss	MIR4646 SAPCD1-AS1 MIR6721 APOM HSPA1B MICA LY6G6F SLC44A4 SKIV2L LST1 ATF6B HLA-B LY6G5C PRRC2A VARS LY6G6C HLA-DRA NCR3 MIR1236 LY6G6E BTNL2 C6orf25 BAG6 TNXB DXO PPT2 MICB AGER EGFL8 MIR6891 SAPCD1 CYP21A1P C2-AS1 FKBPL CFB ATP6V1G2 PBX2 HSPA1L MIR6833 SNORA38 GPANK1 GPSM3 LY6G6D LOC100507547 RNF5 HSPA1A MSH5 MIR6832 SNORD117 CLIC1 C4A LOC102725068 DDX39B LOC101929163 LY6G5B ATP6V1G2-DDX39B C6orf48 STK19 TNXA VWA7 NOTCH4 NFKBIL1 SNORD84 C2 DDX39B-AS1 SNORD52 AGPAT1 TNF MCCD1 LTA ZBTB12 MSH5-SAPCD1 HCG23 LSM2 LTB PPT2-EGFL8 SNORD48 LOC100287329 PRRT1 NELFE CYP21A2 DDAH2 ABHD16A HCG26 AIF1 C4B C6orf47 C6orf10 HCP5 EHMT2 CSNK2B NEU1
nsv1161370	Chr.6:31600692 - 31714252 on Build GRCh38	Deletion	MIR6832 MIR4646 LY6G5B APOM LY6G6F ABHD16A LY6G5C PRRC2A AIF1 SNORA38 C6orf47 GPANK1 LY6G6E CSNK2B BAG6
nsv830627	Chr.6:31528437 - 31692173 on Build GRCh38	Loss	MIR6832 SNORD117 DDX39B LY6G5B ATP6V1G2-DDX39B APOM NFKBIL1 LST1 SNORD84 LY6G5C PRRC2A NCR3 DDX39B-AS1 BAG6 TNF MCCD1 LTA LTB LOC100287329 ATP6V1G2 ABHD16A AIF1 SNORA38 C6orf47 GPANK1 CSNK2B

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

apolipoprotein, transfer/carrier protein, chaperone

Gene Ontology Categories:

Process(es)

retinoid metabolic process
response to glucose
cholesterol efflux
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
negative regulation of plasma lipoprotein particle oxidation
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
cellular oxidant detoxification
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway

Function(s)

lipid transporter activity
phospholipid binding
antioxidant activity
protein binding
Hsp70 protein binding
polyubiquitin binding
ubiquitin protein ligase binding
ribosome binding
misfolded protein binding
proteasome binding
ubiquitin-specific protease binding