Hs06813406_cn

• Gene Symbol: LOC101928140
• Assay Reference Genome Location: Chr.6:128028961 on build GRCh38
• Cytoband: 6q22.33

Target Gene Details

• Entrez Gene ID: 101928140
• Gene Name: uncharacterized LOC101928140
• Gene Aliases: -
• Location: Chr.6:128027865-128086293 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC101928140	NR_125849.1

Target Gene Details

• Entrez Gene ID: 5796
• Gene Name: protein tyrosine phosphatase, receptor type K
• Gene Aliases: R-PTP-kappa
• Location: Chr.6:127968779-128520847 on Build GRCh38
• Assay Gene Location: Within Intron 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPRK	NM_001135648.2			NP_001129120.1
	NM_001291981.1			NP_001278910.1
	NM_001291982.1			NP_001278911.1
	NM_001291983.1			NP_001278912.1
	NM_001291984.1			NP_001278913.1
	NM_002844.3			NP_002835.2
	XM_006715537.2			XP_006715600.1
	XM_011536014.2			XP_011534316.1
	XM_011536015.2			XP_011534317.1
	XM_011536016.2			XP_011534318.1
	XM_011536017.2			XP_011534319.1
	XM_011536018.2			XP_011534320.1
	XM_017011145.1			XP_016866634.1
	XM_017011146.1			XP_016866635.1
	XM_017011147.1			XP_016866636.1
	XM_017011148.1			XP_016866637.1
	AB209670.1			BAD92907.1
	AF533875.1			AAO49502.1
	AK295028.1
	BC140775.1
	BC144512.1
	BC144513.1
	CR749277.1			CAH18132.1
	L77886.1			AAC37599.1
	Z70660.1			CAA94519.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv604642	Chr.6:127957653 - 128029998 on Build GRCh38	Loss	LOC101928140 PTPRK

More Information

Additional Information:

For this assay, SNP(s) [rs73773991] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

protein dephosphorylation
cell adhesion
signal transduction
transforming growth factor beta receptor signaling pathway
negative regulation of cell proliferation
negative regulation of keratinocyte proliferation
cell migration
negative regulation of cell migration
neuron projection development
protein localization to cell surface
cellular response to reactive oxygen species
cellular response to UV
peptidyl-tyrosine dephosphorylation
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
focal adhesion assembly

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
beta-catenin binding
protein kinase binding
gamma-catenin binding