Hs06950777_cn

• Gene Symbol: GRIN2B
• Assay Reference Genome Location: Chr.12:13540197 on build GRCh38
• Cytoband: 12p13.1

Target Gene Details

• Entrez Gene ID: 2904
• Gene Name: glutamate ionotropic receptor NMDA type subunit 2B
• Gene Aliases: EIEE27, GluN2B, MRD6, NMDAR2B, NR2B, hNR3
• Location: Chr.12:13537337-13982012 on Build GRCh38
• Assay Gene Location: Within Exon 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIN2B	XM_005253351.3	4	24947	XP_005253408.1
	XM_011520628.2	14	28013	XP_011518930.1
	XM_011520629.2	15	27820	XP_011518931.1
	XM_017019219.1	14	27568	XP_016874708.1
	BX648060.1	1	136

More Information

Additional Information:

For this assay, SNP(s) [rs73045359] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
transport
glutamate receptor signaling pathway
chemical synaptic transmission
learning or memory
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
positive regulation of GTPase activity
response to ethanol
ephrin receptor signaling pathway

Function(s)

NMDA glutamate receptor activity
Ras guanyl-nucleotide exchange factor activity
extracellular-glutamate-gated ion channel activity
protein binding
zinc ion binding
glycine binding