Hs06972443_cn

• Gene Symbol: LGR5
• Assay Reference Genome Location: Chr.12:71439781 on build GRCh38
• Cytoband: 12q21.1

Target Gene Details

• Entrez Gene ID: 8549
• Gene Name: leucine rich repeat containing G protein-coupled receptor 5
• Gene Aliases: FEX, GPR49, GPR67, GRP49, HG38
• Location: Chr.12:71439770-71586310 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LGR5	NM_001277226.1			NP_001264155.1
	NM_001277227.1			NP_001264156.1
	NM_003667.3			NP_003658.1
	NR_110596.1
	AB105190.1
	AK294985.1
	AK315133.1
	DC323352.1
	DR003044.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762990	Chr.12:71428621 - 71501180 on Build GRCh38	Gain	LGR5
esv2761748	Chr.12:71341747 - 71472405 on Build GRCh38	Gain	LGR5

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

hair follicle development
G-protein coupled receptor signaling pathway
oocyte differentiation
regulation of cell proliferation
inner ear development
positive regulation of canonical Wnt signaling pathway
epithelial cell proliferation involved in renal tubule morphogenesis

Function(s)

transmembrane signaling receptor activity
G-protein coupled receptor activity
protein binding