Hs07066334_cn

• Gene Symbol: AKAP5
• Assay Reference Genome Location: Chr.14:64470952 on build GRCh38
• Cytoband: 14q23.3

Target Gene Details

• Entrez Gene ID: 9495
• Gene Name: A-kinase anchoring protein 5
• Gene Aliases: AKAP75, AKAP79, H21
• Location: Chr.14:64465499-64474503 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AKAP5	NM_004857.3	2	2936	NP_004848.3

Target Gene Details

• Entrez Gene ID: 7597
• Gene Name: zinc finger and BTB domain containing 25
• Gene Aliases: C14orf51, KUP, ZNF46
• Location: Chr.14:64447172-64505213 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZBTB25	NM_001304508.1			NP_001291437.1
	XM_006720250.3			XP_006720313.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952852	Chr.14:64465983 - 64475282 on Build GRCh38	Duplication	ZBTB25 AKAP5
esv2748779	Chr.14:63663324 - 66595809 on Build GRCh38	Deletion	LINC00238 SGPP1 SYNE2 MIR7855 AKAP5 PLEKHG3 ZBTB1 FNTB CHURC1 TEX21P SPTB LOC100506321 CHURC1-FNTB FUT8 MIR4708 MIR4706 LOC102723809 GPX2 MIR548H1 ESR2 MIR625 RAB15 PPP1R36 ZBTB25 LOC100128233 GPHN FUT8-AS1 MTHFD1 HSPA2 MAX

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein, C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
protein targeting
signal transduction
negative regulation of adenylate cyclase activity
chemical synaptic transmission
positive regulation of calcium ion transport into cytosol
positive regulation of protein kinase A signaling
response to muscle activity
spinal cord development
hippocampus development
positive regulation of cAMP biosynthetic process
amylase secretion
negative regulation of potassium ion transport
cellular protein complex disassembly
positive regulation of adenylate cyclase activity
positive regulation of dendrite morphogenesis
positive regulation of NFAT protein import into nucleus
response to electrical stimulus
maternal process involved in female pregnancy
cellular response to organonitrogen compound
transcription, DNA-templated
regulation of transcription, DNA-templated
gene expression

Function(s)

G-protein coupled receptor binding
actin binding
protein binding
calmodulin binding
adenylate cyclase binding
protein kinase binding
protein domain specific binding
protein phosphatase 2B binding
protein complex binding
protein kinase A regulatory subunit binding
cadherin binding
GABA receptor binding
protein kinase A binding
DNA binding
transcription factor activity, sequence-specific DNA binding
metal ion binding