Hs07122316_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54150580 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Within Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1			BAD18729.1
	AK300434.1
	AL133647.1			CAB63766.1
	BC016474.1			AAH16474.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	MBOAT7 LENG1 NDUFA3 TFPT PRPF31 TMC4 CNOT3
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	MBOAT7 LENG1 OSCAR NDUFA3 TSEN34 TFPT PRPF31 TMC4 CNOT3
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	OSCAR MIR1283-2 TSEN34 MIR520H MIR518C MIR519A2 MIR520B MIR519E MIR523 DPRX LILRB5 MIR518D MIR498 TARM1 LENG1 MIR517B MIR512-1 VN1R2 ZNF331 TFPT BIRC8 MIR520F ZNF818P MIR520D MIR512-2 ZNF765 MIR516A2 RPS9 MIR518E MIR517C MIR526A1 MIR519A1 MIR524 MBOAT7 MIR371B MIR518A2 MIR516B1 MIR517A ZNF761 LILRA5 MIR372 MIR515-2 MIR518F MYADM CNOT3 MIR4752 MIR525 LILRB3 MIR1283-1 MIR519C MIR515-1 ZNF813 ZNF525 MIR373 VN1R4 VSTM1 MIR521-1 MIR526B CACNG7 MIR520G MIR371A CACNG8 PRKCG MIR518B MIR522 MIR520E MIR516A1 MIR526A2 MIR521-2 MIR520C MIR520A LOC284379 LILRA6 CACNG6 MIR527 LILRB2 MIR519B MIR518A1 FAM90A27P MIR519D PRPF31 LOC105372457 MIR935 TMC4 ZNF665 ZNF677 NDUFA3 ZNF845 MIR516B2 TPM3P9 MIR1323 NLRP12

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding