Hs07133407_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54150015 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Within Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1			BAD18729.1
	AK300434.1
	AL133647.1			CAB63766.1
	BC016474.1			AAH16474.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	TMC4 PRPF31 MBOAT7 TFPT LENG1 CNOT3 NDUFA3
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	TSEN34 TMC4 OSCAR PRPF31 MBOAT7 TFPT LENG1 CNOT3 NDUFA3
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	ZNF525 OSCAR MIR519D LOC105372457 MIR518D MIR516A2 VN1R4 MIR520F MIR526A2 VSTM1 MIR518C LILRB3 MIR520B MIR523 MIR515-1 MIR516B2 FAM90A27P PRKCG CNOT3 ZNF761 TARM1 LILRB5 MIR516B1 MIR521-1 MIR371B MIR372 MIR527 MIR518A2 MIR520D DPRX MIR519E MIR512-1 MIR1283-1 MIR1283-2 ZNF677 MIR4752 MIR522 TPM3P9 PRPF31 MIR518E LENG1 MIR516A1 MIR520H BIRC8 CACNG8 MYADM MIR371A MIR935 MIR517C MIR517A LILRB2 LILRA6 ZNF331 MIR518B NDUFA3 MIR520E NLRP12 LOC284379 ZNF818P LILRA5 MBOAT7 TFPT MIR520C MIR519B MIR518A1 VN1R2 MIR526A1 MIR526B TMC4 MIR525 RPS9 MIR517B MIR519A2 MIR519A1 MIR524 CACNG7 MIR1323 MIR518F MIR498 ZNF665 ZNF813 MIR373 TSEN34 MIR520A ZNF765 CACNG6 MIR520G MIR519C MIR515-2 MIR521-2 ZNF845 MIR512-2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding