Hs07155286_cn

• Gene Symbol: PAK4
• Assay Reference Genome Location: Chr.19:39156038 on build GRCh38
• Cytoband: 19q13.2

Target Gene Details

• Entrez Gene ID: 10298
• Gene Name: p21 (RAC1) activated kinase 4
• Gene Aliases: -
• Location: Chr.19:39125780-39179406 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PAK4	NM_001014831.2			NP_001014831.1
	NM_001014832.1			NP_001014832.1
	NM_001014834.2			NP_001014834.1
	NM_001014835.1			NP_001014835.1
	NM_005884.3			NP_005875.1
	XM_011526316.1			XP_011524618.1
	XM_011526320.1			XP_011524622.1
	AB032968.1
	AF005046.1			AAD01210.1
	AK291839.1
	AK293517.1
	AK294586.1
	AK300632.1
	AK304651.1
	AL834236.1			CAD38914.2
	AX775863.1			CAE11631.1
	AX775865.1			CAE11632.1
	AX775867.1			CAE11633.1
	AX775869.1			CAE11634.1
	AX775871.1			CAE11635.1
	BC002921.2			AAH02921.1
	BC011368.1			AAH11368.1
	BC025282.1			AAH25282.1
	BC034511.1			AAH34511.1
	BG773480.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953571	Chr.19:39152861 - 39222260 on Build GRCh38	Deletion	SYCN NCCRP1 PAK4
nsv833829	Chr.19:39079041 - 39240137 on Build GRCh38	Loss	SYCN NCCRP1 PAK4 ACP7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

mitotic cell cycle
apoptotic process
movement of cell or subcellular component
cytoskeleton organization
signal transduction
cell proliferation
cell growth
cell migration
signal transduction by protein phosphorylation
dendritic spine development
cellular response to organic cyclic compound
cell-cell adhesion

Function(s)

protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
cadherin binding involved in cell-cell adhesion