Hs07156857_cn

• Gene Symbol: NCR1
• Assay Reference Genome Location: Chr.19:54928596 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 9437
• Gene Name: natural cytotoxicity triggering receptor 1
• Gene Aliases: CD335, LY94, NK-p46, NKP46
• Location: Chr.19:54906042-54938211 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NCR1	XM_011527530.2			XP_011525832.1

Target Gene Details

• Entrez Gene ID: 199713
• Gene Name: NLR family pyrin domain containing 7
• Gene Aliases: CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3
• Location: Chr.19:54923509-54965184 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NLRP7	NM_001127255.1			NP_001120727.1
	NM_139176.3			NP_631915.2
	NM_206828.3			NP_996611.2
	XM_006723075.3			XP_006723138.1
	XM_006723076.3			XP_006723139.1
	XM_011526596.2			XP_011524898.1
	XM_011526599.2			XP_011524901.1
	XM_011526601.2			XP_011524903.1
	AF464765.1			AAL69963.1
	AK298630.1
	AK302655.1
	AK313964.1
	AY154462.1			AAO18158.1
	BC109124.2			AAI09125.1
	BC109125.1			AAI09126.1
	BX363944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv520644	Chr.19:54889804 - 54940429 on Build GRCh38	Loss	FCAR NLRP7 NCR1
esv2667609	Chr.19:54472514 - 55094226 on Build GRCh38	Deletion	LOC101928804 PPP1R12C NLRP7 KIR2DS4 KIR3DX1 KIR3DL1 EPS8L1 MIR8061 LILRB1 KIR3DL3 FCAR NLRP2 LILRP2 LOC102724300 LILRB4 KIR3DL2 NCR1 GP6 LILRA1 KIR2DL1 LAIR2 KIR2DL3 RDH13 LILRA2 KIR2DL4 CDC42EP5
nsv1062047	Chr.19:54921092 - 55041328 on Build GRCh38	Gain	NLRP7 NLRP2 RDH13 NCR1 GP6
nsv428372	Chr.19:54596370 - 54954956 on Build GRCh38	Gain+Loss	KIR3DL3 LOC101928804 FCAR NLRP7 KIR2DS4 LILRP2 LOC102724300 LILRB4 KIR3DL2 KIR3DL1 NCR1 LILRA1 KIR2DL1 MIR8061 KIR2DL3 LILRB1 KIR2DL4
esv2758771	Chr.19:54163847 - 54954956 on Build GRCh38	Gain+Loss	MBOAT7 LOC101928804 RPS9 NLRP7 KIR2DS4 KIR3DX1 TSEN34 KIR3DL1 LILRA5 LILRB5 LENG8-AS1 LENG8 LILRB3 LAIR1 MIR8061 LILRB1 LILRA6 KIR3DL3 FCAR LILRP2 LOC102724300 LILRB4 KIR3DL2 MIR4752 TTYH1 TMC4 NCR1 LILRA1 KIR2DL1 LILRA4 LAIR2 LILRB2 KIR2DL3 LENG9 LILRA2 KIR2DL4 CDC42EP5
nsv833880	Chr.19:54889952 - 55067343 on Build GRCh38	Loss	FCAR NLRP7 NLRP2 RDH13 NCR1 GP6
esv2718872	Chr.19:54472594 - 55094247 on Build GRCh38	Deletion	LOC101928804 PPP1R12C NLRP7 KIR2DS4 KIR3DX1 KIR3DL1 EPS8L1 MIR8061 LILRB1 KIR3DL3 FCAR NLRP2 LILRP2 LOC102724300 LILRB4 KIR3DL2 NCR1 GP6 LILRA1 KIR2DL1 LAIR2 KIR2DL3 RDH13 LILRA2 KIR2DL4 CDC42EP5
esv3893250	Chr.19:54906374 - 55000768 on Build GRCh38	Loss	NLRP7 NLRP2 NCR1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily, non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

cellular defense response
signal transduction
natural killer cell activation
regulation of natural killer cell mediated cytotoxicity
regulation of immune response

Function(s)

receptor signaling protein activity
ATP binding