Hs07181960_cn

• Gene Symbol: PTPRA
• Assay Reference Genome Location: Chr.20:2872599 on build GRCh38
• Cytoband: 20p13

Target Gene Details

• Entrez Gene ID: 5786
• Gene Name: protein tyrosine phosphatase, receptor type A
• Gene Aliases: HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
• Location: Chr.20:2864195-3038669 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPRA	NM_002836.3			NP_002827.1
	M34668.1			AAA36528.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3262	Chr.20:2872560 - 2893089 on Build GRCh38	Insertion	PTPRA
esv3645020	Chr.20:2816405 - 2926274 on Build GRCh38	Gain	TMEM239 VPS16 PTPRA PCED1A
nsv1057464	Chr.20:2650623 - 2989686 on Build GRCh38	Gain	SNORD57 SNORD86 SNORA51 IDH3B TMEM239 EBF4 C20orf141 MIR1292 NOP56 VPS16 SNORD110 PTPRA CPXM1 PCED1A SNORD56
nsv522009	Chr.20:2745032 - 3030542 on Build GRCh38	Gain	C20orf141 TMEM239 VPS16 EBF4 PTPRA CPXM1 PCED1A
nsv833895	Chr.20:2730164 - 2882236 on Build GRCh38	Loss	C20orf141 TMEM239 VPS16 EBF4 PTPRA CPXM1 PCED1A
esv2762056	Chr.20:2740745 - 2944353 on Build GRCh38	Gain	C20orf141 TMEM239 VPS16 EBF4 PTPRA CPXM1 PCED1A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

MAPK cascade
axon guidance
insulin receptor signaling pathway
peptidyl-tyrosine dephosphorylation
positive regulation of GTPase activity

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
Ras guanyl-nucleotide exchange factor activity
protein binding