Hs07396832_cn

• Gene Symbol: TBK1
• Assay Reference Genome Location: Chr.12:64452346 on build GRCh38
• Cytoband: 12q14.2

Target Gene Details

• Entrez Gene ID: 29110
• Gene Name: TANK binding kinase 1
• Gene Aliases: FTDALS4, NAK, T2K
• Location: Chr.12:64452060-64502119 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBK1	NM_013254.3			NP_037386.1
	XM_005268809.1			XP_005268866.1
	AF191838.1			AAF05989.1
	AK291039.1
	BC034950.2			AAH34950.1
	DA788357.1

More Information

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

inflammatory response
I-kappaB kinase/NF-kappaB signaling
response to virus
negative regulation of gene expression
peptidyl-serine phosphorylation
negative regulation of type I interferon production
positive regulation of type I interferon production
type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of peptidyl-serine phosphorylation
TRIF-dependent toll-like receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
dendritic cell proliferation
innate immune response
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
defense response to Gram-positive bacterium
defense response to virus
regulation of neuron death
positive regulation of xenophagy

Function(s)

nucleic acid binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
phosphoprotein binding