Mm00028331_cn

• Gene Symbol: Hdac4
• Assay Reference Genome Location: Chr.1:91996159 on build GRCm38
• Cytoband: 1D

Target Gene Details

• Entrez Gene ID: 208727
• Gene Name: histone deacetylase 4
• Gene Aliases: 4932408F19Rik, AI047285
• Location: Chr.1:91928779-92180385 on Build GRCm38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Hdac4	NM_207225.1			NP_997108.1
	AK029933.1			BAE43272.1
	AK155250.1			BAE33147.1
	BC066052.1			AAH66052.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
osteoblast development
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of lamellipodium assembly
negative regulation of myotube differentiation
regulation of cardiac muscle contraction by calcium ion signaling
response to denervation involved in regulation of muscle adaptation
positive regulation of smooth muscle cell migration
chromatin modification
histone deacetylation
positive regulation of protein sumoylation
peptidyl-lysine deacetylation
regulation of gene expression, epigenetic
response to drug
regulation of protein binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of osteoblast differentiation
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
regulation of skeletal muscle fiber development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of striated muscle cell differentiation
response to interleukin-1
histone H3 deacetylation
histone H4 deacetylation
positive regulation of reactive oxygen species biosynthetic process

Function(s)

RNA polymerase III transcription factor binding
core promoter binding
DNA binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
zinc ion binding
hydrolase activity
protein kinase binding
potassium ion binding
histone deacetylase activity (H3-K14 specific)
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
activating transcription factor binding
histone deacetylase activity (H4-K16 specific)
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
repressing transcription factor binding
NAD-dependent histone deacetylase activity (H3-K18 specific)