Mm00547257_cn

• Gene Symbol: Nfkb1
• Assay Reference Genome Location: Chr.3:135691478 on build GRCm38
• Cytoband: 3G3

Target Gene Details

• Entrez Gene ID: 18033
• Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
• Gene Aliases: NF-KB1, NF-kappaB, NF-kappaB1, p105, p50, p50/p105
• Location: Chr.3:135584655-135691547 on Build GRCm38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Nfkb1	NM_008689.2	1	70	NP_032715.2
	BC050841.1	1	70	AAH50841.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine production
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
inflammatory response
response to oxidative stress
signal transduction
I-kappaB kinase/NF-kappaB signaling
negative regulation of calcidiol 1-monooxygenase activity
response to cytokine
response to muscle stretch
NIK/NF-kappaB signaling
negative regulation of apoptotic process
negative regulation of interleukin-12 biosynthetic process
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lymph node development
negative regulation of inflammatory response
cellular response to lipopolysaccharide
cellular response to nicotine
cellular response to interleukin-6
cellular response to dsRNA
cellular response to peptide hormone stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of hyaluronan biosynthetic process
positive regulation of miRNA metabolic process

Function(s)

regulatory region DNA binding
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
heat shock protein binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity