Mm00587182_cn

• Gene Symbol: Ascl1
• Assay Reference Genome Location: Chr.10:87491197 on build GRCm38
• Cytoband: 10C1

Target Gene Details

• Entrez Gene ID: 17172
• Gene Name: achaete-scute complex homolog 1 (Drosophila)
• Gene Aliases: AI225900, ASH1, Mash1, bHLHa46
• Location: Chr.10:87491041-87493660 on Build GRCm38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ascl1	NM_008553.4	2	2103	NP_032579.2
	AK143210.1	2	2104	BAE25307.1
	BC055748.1	2	1625	AAH55748.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
noradrenergic neuron development
noradrenergic neuron fate commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
regulation of mitotic cell cycle
pattern specification process
nervous system development
neuroblast fate determination
neuroblast proliferation
regulation of Notch signaling pathway
glial cell differentiation
regulation of gene expression
oligodendrocyte development
spinal cord association neuron differentiation
spinal cord oligodendrocyte cell differentiation
spinal cord oligodendrocyte cell fate specification
vestibular nucleus development
oligodendrocyte cell fate commitment
forebrain neuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
central nervous system neuron development
cerebral cortex development
neurogenesis
cell differentiation
neuron differentiation
regulation of epithelial cell differentiation
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
enteric nervous system development
sympathetic nervous system development
parasympathetic nervous system development
neuron fate commitment
neuron fate specification
neuron development
generation of neurons
oligodendrocyte differentiation
regulation of neurogenesis
positive regulation of neurogenesis
musculoskeletal movement, spinal reflex action
subpallium neuron fate commitment
regulation of timing of subpallium neuron differentiation
olfactory pit development
ventral spinal cord interneuron fate commitment
lung neuroendocrine cell differentiation
stomach neuroendocrine cell differentiation
carotid body glomus cell differentiation
adrenal chromaffin cell differentiation
sympathetic ganglion development
positive regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein homodimerization activity
bHLH transcription factor binding
sequence-specific DNA binding
protein dimerization activity
E-box binding