Mm00593006_cn

• Gene Symbol: Nodal
• Assay Reference Genome Location: Chr.10:61418232 on build GRCm38
• Cytoband: 10B4

Target Gene Details

• Entrez Gene ID: 18119
• Gene Name: nodal
• Gene Aliases: Tg.413d
• Location: Chr.10:61417972-61425337 on Build GRCm38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Nodal	NM_013611.4	1	261	NP_038639.2
	X70514.1	1	261	CAA49914.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
gastrulation with mouth forming second
mesoderm formation
trophectodermal cell differentiation
trophectodermal cellular morphogenesis
neural fold formation
liver development
placenta development
embryonic placenta development
maternal placenta development
vasculature development
heart looping
inhibition of neuroepithelial cell differentiation
transforming growth factor beta receptor signaling pathway
multicellular organism development
determination of left/right symmetry
gastrulation
nervous system development
brain development
endoderm development
heart development
positive regulation of cell proliferation
embryonic pattern specification
anterior/posterior axis specification
anterior/posterior pattern specification
regulation of signal transduction
polarity specification of proximal/distal axis
regulation of gastrulation
positive regulation of vascular endothelial growth factor production
negative regulation of cell development
positive regulation of pathway-restricted SMAD protein phosphorylation
cell migration
stem cell population maintenance
positive regulation of cell-cell adhesion
lung development
positive regulation of activin receptor signaling pathway
floor plate morphogenesis
embryonic heart tube development
endodermal cell differentiation
nodal signaling pathway
growth
cell migration involved in gastrulation
regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of MAPK cascade
cell fate commitment
negative regulation of cell differentiation
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
axial mesodermal cell fate specification
mesendoderm development
cell development
digestive tract morphogenesis
anatomical structure formation involved in morphogenesis
embryonic cranial skeleton morphogenesis
tissue morphogenesis
formation of anatomical boundary
positive regulation of epithelial cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
digestive system development
embryonic process involved in female pregnancy
maternal process involved in parturition
positive regulation of SMAD protein import into nucleus
SMAD protein signal transduction
left lung morphogenesis
negative regulation of androgen receptor signaling pathway
epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
positive regulation of ERK1 and ERK2 cascade
primitive streak formation
transforming growth factor beta receptor signaling pathway involved in primitive streak formation
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of trophoblast cell migration
negative regulation of chorionic trophoblast cell proliferation
positive regulation of receptor activity

Function(s)

cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
receptor agonist activity
type I activin receptor binding