Hs00301229_cn

• Gene Symbol: ARNT
• Assay Reference Genome Location: Chr.1:150829956 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 405
• Gene Name: aryl hydrocarbon receptor nuclear translocator
• Gene Aliases: HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2
• Location: Chr.1:150809705-150876768 on Build GRCh38
• Assay Gene Location: Overlaps Intron 13 - Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARNT	NM_001197325.1			NP_001184254.1
	NM_001286035.1			NP_001272964.1
	NM_001286036.1			NP_001272965.1
	NM_001668.3			NP_001659.1
	NM_178427.2			NP_848514.1
	XM_005245151.1			XP_005245208.1
	XM_005245153.1			XP_005245210.1
	XM_005245154.3			XP_005245211.1
	XM_005245157.1			XP_005245214.1
	XM_011509542.2			XP_011507844.1
	XM_011509543.2			XP_011507845.1
	XM_011509544.2			XP_011507846.1
	XM_011509545.2			XP_011507847.1
	XM_011509546.1			XP_011507848.1
	XM_011509547.2			XP_011507849.1
	XM_017001288.1			XP_016856777.1
	XM_017001289.1			XP_016856778.1
	XM_017001290.1			XP_016856779.1
	XM_017001291.1			XP_016856780.1
	XM_017001292.1			XP_016856781.1
	XM_017001293.1			XP_016856782.1
	XM_017001294.1			XP_016856783.1
	XM_017001295.1			XP_016856784.1
	XM_017001296.1			XP_016856785.1
	AB209877.1			BAD93114.1
	AF001307.1			AAC03365.1
	AK290177.1
	AK291705.1
	AK293027.1
	AK304772.1
	AK313780.1
	AK315812.1
	AL834279.1			CAD38953.1
	M69238.1			AAA51777.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1010875	Chr.1:150824340 - 150873351 on Build GRCh38	Gain	ARNT
nsv437169	Chr.1:150765721 - 150844410 on Build GRCh38	Loss	CTSK CTSS ARNT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

response to hypoxia
embryonic placenta development
positive regulation of endothelial cell proliferation
transcription, DNA-templated
positive regulation of vascular endothelial growth factor production
cell differentiation
intracellular receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein sumoylation
mRNA transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
positive regulation of erythrocyte differentiation
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone biosynthetic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
aryl hydrocarbon receptor activity
protein binding
transcription factor binding
aryl hydrocarbon receptor binding
enhancer binding
sequence-specific DNA binding
protein heterodimerization activity