Hs02814470_cn

• Gene Symbol: ARNT
• Assay Reference Genome Location: Chr.1:150810487 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 405
• Gene Name: aryl hydrocarbon receptor nuclear translocator
• Gene Aliases: HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2
• Location: Chr.1:150809705-150876768 on Build GRCh38
• Assay Gene Location: Within Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARNT	NM_001197325.1	21	4057	NP_001184254.1
	NM_001286035.1	23	4146	NP_001272964.1
	NM_001286036.1	22	4099	NP_001272965.1
	NM_001668.3	22	4105	NP_001659.1
	NM_178427.2	21	4060	NP_848514.1
	XM_005245151.1	22	4044	XP_005245208.1
	XM_005245153.1	22	4032	XP_005245210.1
	XM_005245154.3	23	4075	XP_005245211.1
	XM_005245157.1	21	3936	XP_005245214.1
	XM_011509542.2	22	4108	XP_011507844.1
	XM_011509543.2	23	4103	XP_011507845.1
	XM_011509544.2	22	4072	XP_011507846.1
	XM_011509545.2	21	4063	XP_011507847.1
	XM_011509546.1	21	3823	XP_011507848.1
	XM_011509547.2	21	4060	XP_011507849.1
	XM_017001288.1	23	3947	XP_016856777.1
	XM_017001289.1	23	3935	XP_016856778.1
	XM_017001290.1	22	3904	XP_016856779.1
	XM_017001291.1	22	3903	XP_016856780.1
	XM_017001292.1	22	3840	XP_016856781.1
	XM_017001293.1	21	3794	XP_016856782.1
	XM_017001294.1	21	3933	XP_016856783.1
	XM_017001295.1	21	3921	XP_016856784.1
	XM_017001296.1	20	3900	XP_016856785.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv437169	Chr.1:150765721 - 150844410 on Build GRCh38	Loss	CTSS CTSK ARNT
nsv2788	Chr.1:150782858 - 150828309 on Build GRCh38	Deletion	CTSK ARNT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

response to hypoxia
embryonic placenta development
positive regulation of endothelial cell proliferation
transcription, DNA-templated
positive regulation of vascular endothelial growth factor production
cell differentiation
intracellular receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein sumoylation
mRNA transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
positive regulation of erythrocyte differentiation
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone biosynthetic process
regulation of transcription from RNA polymerase II promoter in response to hypoxia

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
aryl hydrocarbon receptor activity
protein binding
transcription factor binding
aryl hydrocarbon receptor binding
enhancer binding
sequence-specific DNA binding
protein heterodimerization activity