Hs03069553_cn

• Gene Symbol: LIME1
• Assay Reference Genome Location: Chr.20:63735942 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 54923
• Gene Name: Lck interacting transmembrane adaptor 1
• Gene Aliases: LIME, dJ583P15.4
• Location: Chr.20:63735701-63739107 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LIME1	NM_001305654.1	1	242	NP_001292583.1
	AY203957.1	1	242	AAP34480.1

Target Gene Details

• Entrez Gene ID: 84619
• Gene Name: zinc finger CCCH-type and G-patch domain containing
• Gene Aliases: GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP
• Location: Chr.20:63707442-63736142 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZGPAT	NM_001083113.1	7	1705	NP_001076582.1
	NM_001195653.1	7	1729	NP_001182582.1
	NM_001195654.1	7	1721	NP_001182583.1
	NM_032527.4	7	1808	NP_115916.3
	NM_181485.2	7	1678	NP_852150.2
	AB058750.3	7	1682
	AK027878.1	7	1746	BAB55426.1
	AK074961.1	6	2632	BAC11317.1
	AK307368.1	3	613
	AK314726.1
	BC019338.1	7	1696	AAH19338.1
	BC032612.1	7	1668	AAH32612.1
	KU178806.1
	KU178807.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2722959	Chr.20:63715664 - 63806918 on Build GRCh38	Deletion	ZBTB46 LIME1 SLC2A4RG ZGPAT
nsv953308	Chr.20:63650148 - 63831847 on Build GRCh38	Deletion	RTEL1-TNFRSF6B ARFRP1 ZBTB46 RTEL1 LIME1 STMN3 TNFRSF6B SLC2A4RG ZGPAT ZBTB46-AS1
nsv586614	Chr.20:63725275 - 63741460 on Build GRCh38	Gain	LIME1 SLC2A4RG ZGPAT
nsv1139762	Chr.20:63731048 - 63737647 on Build GRCh38	Duplication	LIME1 ZGPAT
nsv1160690	Chr.20:63639552 - 63744287 on Build GRCh38	Deletion	RTEL1-TNFRSF6B ARFRP1 ZBTB46 RTEL1 LIME1 STMN3 TNFRSF6B SLC2A4RG ZGPAT
nsv428381	Chr.20:63583375 - 64334167 on Build GRCh38	Gain+Loss	MIR941-3 RTEL1-TNFRSF6B SOX18 OPRL1 MIR941-5 ZGPAT LKAAEAR1 MYT1 C20orf181 PCMTD2 MIR1914 LIME1 UCKL1-AS1 MIR941-2 LINC00176 SLC2A4RG MIR647 MIR941-4 SAMD10 ZBTB46-AS1 GMEB2 ARFRP1 ZNF512B ABHD16B PRPF6 NPBWR2 TCEA2 MIR6813 UCKL1 ZBTB46 LINC00266-1 RTEL1 LOC100505771 DNAJC5 STMN3 TNFRSF6B MIR941-1 TPD52L2 RGS19
esv7227	Chr.20:63715550 - 63807161 on Build GRCh38	Loss	ZBTB46 LIME1 SLC2A4RG ZGPAT
nsv1059142	Chr.20:63731978 - 63798885 on Build GRCh38	Gain	ZBTB46 LIME1 SLC2A4RG ZGPAT
nsv586615	Chr.20:63734204 - 63741603 on Build GRCh38	Gain	LIME1 SLC2A4RG ZGPAT
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	GMEB2 RTEL1-TNFRSF6B ARFRP1 FNDC11 ZGPAT EEF1A2 PTK6 ZBTB46 RTEL1 LOC100505771 SRMS LIME1 HELZ2 PPDPF STMN3 TNFRSF6B SLC2A4RG
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	GMEB2 RTEL1-TNFRSF6B ARFRP1 FNDC11 ZGPAT EEF1A2 KCNQ2 PTK6 ZBTB46 RTEL1 LOC100505771 SRMS LIME1 HELZ2 PPDPF STMN3 TNFRSF6B SLC2A4RG

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

adaptive immune response
T cell receptor signaling pathway
B cell receptor signaling pathway
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of epidermal growth factor-activated receptor activity
negative regulation of transcription, DNA-templated

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding