Hs04334470_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76356147 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	FDPSP2 YWHAG POMZP3 DTX2 DTX2P1-UPK3BP1-PMS2P11 SPDYE16 SRRM3 SSC4D ZP3 HSPB1 LOC100133091 LOC105375355
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	YWHAG STAG3L1 POM121C STYXL1 SPDYE16 CCL26 TMEM120A SSC4D HSPB1 HIP1 POMZP3 GTF2IP1 MDH2 CCL24 GTF2IRD2B LOC441259 POR LOC105375355 TRIM73 FDPSP2 NCF1C PMS2P2 RHBDD2 LOC541473 SRRM3 LOC107986711 PMS2P10 GTF2IP7 ZP3 SNORA14A PMS2P3 DTX2 NSUN5P1 SPDYE5 MIR4651 LOC100133091
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	FDPSP2 SPDYE18 YWHAG SPDYE16 PMS2P9 SSC4D ZP3 POMZP3 DTX2 DTX2P1-UPK3BP1-PMS2P11 CCDC146 LOC100133091 LOC105375355 FGL2 SPDYE17
nsv1148733	Chr.7:76353392 - 76365602 on Build GRCh38	Deletion	YWHAG
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	YWHAG SSC4D ZP3
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	YWHAG POM121C STYXL1 SPDYE16 CCL26 TMEM120A SSC4D HSPB1 HIP1 POMZP3 MDH2 CCL24 POR LOC105375355 FDPSP2 RHBDD2 SRRM3 LOC107986711 GTF2IP7 ZP3 SNORA14A PMS2P3 DTX2 SPDYE5 MIR4651 LOC100133091

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding