Hs00152932_m1

• Gene Symbol: TLR2
• Gene Name: toll like receptor 2
• Gene Aliases: CD282, TIL4
• Chromosome Location: Chr.4: 153684080 - 153710643 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TLR2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001318789.1	NP_001305718.1	2 - 3	256		80
	NM_001318790.1	NP_001305719.1	2 - 3	233		80
	NM_001318791.1	NP_001305720.1	2 - 3	222		80
	NM_001318793.1	NP_001305722.1	2 - 3	218		80
	NM_003264.4	NP_003255.2	2 - 3	241		80
GenBank mRNA	AF051152.1	-	1 - 2	147		80
	BI769109.1	-	2 - 3	204		80
	DA460298.1	-	3 - 4	207		80
	U88878.1	-	1 - 2	114		80

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0400009048.hg.1
This assay targets the same location as HTA transcript cluster(s) TC04000775.hg.1

Additional Information:

This assay is in the 5'UTR region of the AF051152.1,NM_001318789.1,NM_001318790.1,NM_001318791.1,NM_001318793.1,NM_003264.4,U88878.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, Human NFkB Pathway, Inventoried, Human_Nfkb, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TLR2

Gene Ontology Categories:

Process(es)

cytokine secretion involved in immune response
MyD88-dependent toll-like receptor signaling pathway
apoptotic process
inflammatory response
immune response
signal transduction
I-kappaB phosphorylation
positive regulation of gene expression
positive regulation of Wnt signaling pathway
lipopolysaccharide-mediated signaling pathway
interleukin-10 production
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor TLR1:TLR2 signaling pathway
toll-like receptor TLR6:TLR2 signaling pathway
positive regulation of NF-kappaB import into nucleus
detection of triacyl bacterial lipopeptide
detection of diacyl bacterial lipopeptide
innate immune response
positive regulation of transcription from RNA polymerase II promoter
regulation of cytokine secretion
positive regulation of inflammatory response
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
cellular response to diacyl bacterial lipopeptide
cellular response to triacyl bacterial lipopeptide

Function(s)

lipopolysaccharide binding
lipopolysaccharide receptor activity
receptor activity
transmembrane signaling receptor activity
protein binding
signaling pattern recognition receptor activity
Toll-like receptor binding
triacyl lipopeptide binding
peptidoglycan binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR04010696.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04010696.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04010696.hg.1	TC04000775.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR0400162111.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162111.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162111.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162111.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162111.hg.1	TC0400009048.hg.1	Clariom D TC