Hs00998449_m1

• Gene Symbol: KMT2B
• Gene Name: lysine methyltransferase 2B
• Gene Aliases: CXXC10, HRX2, MLL1B, MLL2, MLL4, TRX2, WBP-7, WBP7
• Chromosome Location: Chr.19: 35717818 - 35738880 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KMT2B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_014727.2	NP_055542.1	22 - 23	4918		76
	XM_011527561.2	XP_011525863.2	22 - 23	4789		76
	XM_011527562.2	XP_011525864.1	22 - 23	5119		76
	XM_017027544.1	XP_016883033.1	22 - 23	5119		76
	XM_017027545.1	XP_016883034.1	21 - 22	4832		76
	XM_017027546.1	XP_016883035.1	17 - 18	2040		76
GenBank mRNA	AB002302.3	-	20 - 21	4018		76
	AF104918.1	-	20 - 21	2932		76
	AF186605.1	-	22 - 23	4590		76
	AJ007041.1	-	22 - 23	4918		76

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1900007878.hg.1
This assay targets the same location as HTA transcript cluster(s) TC19000483.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KMT2B

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

ovarian follicle development
transcription, DNA-templated
memory
oocyte differentiation
gene silencing
ovulation
chromatin-mediated maintenance of transcription
histone H3-K4 methylation
regulation of histone H3-K4 methylation
histone H3-K4 trimethylation

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR19006364.hg.1	ENST00000222270.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR19006364.hg.1	ENST00000420124.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR19006364.hg.1	NM_014727.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR19006364.hg.1	TC19000483.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	ENST00000420124.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	ENST00000607650.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	NM_014727.2	Refseq
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	TC1900007878.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	ENST00000420124.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	ENST00000607650.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1900158501.hg.1	NM_014727.2	Refseq