Hs01046326_m1

• Gene Symbol: BTRC
• Gene Name: beta-transducin repeat containing E3 ubiquitin protein ligase
• Gene Aliases: BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
• Chromosome Location: Chr.10: 101353808 - 101557321 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: BTRC
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003939.4	NP_003930.1	2 - 3	276		126
	NM_033637.3	NP_378663.1	3 - 4	384		126
	XM_006718054.2	XP_006718117.1	3 - 4	684		126
	XM_017016871.1	XP_016872360.1	3 - 4	275		126
	XM_017016872.1	XP_016872361.1	3 - 4	447		126
	XM_017016873.1	XP_016872362.1	3 - 4	303		126
GenBank mRNA	AF101784.1	-	3 - 4	236		126
	AF129530.1	-	2 - 3	197		126
	AK313353.1	-	3 - 4	257		126
	AK313417.1	-	2 - 3	240		126
	AL707686.1	-	3 - 4	353		126
	BC027994.1	-	3 - 4	273	5180993	126
	GU727631.1	-	3 - 4	273		126
	KU178451.1	-	3 - 4	236		126
	KU178452.1	-	5 - 6	385		126
	KU178453.1	-	4 - 5	329		126
	Y14153.1	-	2 - 3	197		126

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC10000738.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene BTRC

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein dephosphorylation
ubiquitin-dependent protein catabolic process
signal transduction
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
mammary gland epithelial cell proliferation
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
regulation of circadian rhythm
positive regulation of circadian rhythm
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of proteolysis
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
branching involved in mammary gland duct morphogenesis
regulation of canonical Wnt signaling pathway
regulation of proteasomal protein catabolic process
cellular response to organic cyclic compound

Function(s)

ubiquitin-protein transferase activity
protein binding
beta-catenin binding
ligase activity
protein phosphorylated amino acid binding
protein dimerization activity
ubiquitin protein ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	ENST00000370187.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	ENST00000393441.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	ENST00000408038.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	ENST00000539411.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	NM_003939.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	NM_033637.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR10008708.hg.1	TC10000738.hg.1	HTA TC