Hs01061877_m1

• Gene Symbol: DOCK1
• Gene Name: dedicator of cytokinesis 1
• Gene Aliases: DOCK180, ced5
• Chromosome Location: Chr.10: 126905409 - 127452517 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DOCK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001290223.1	NP_001277152.1	32 - 33	3395		97
	NM_001380.4	NP_001371.1	32 - 33	3332		97
	XM_011539422.2	XP_011537724.1	32 - 33	3373		97
	XM_011539424.1	XP_011537726.1	32 - 33	3283		97
	XM_017015813.1	XP_016871302.1	32 - 33	3305		97
	XM_017015816.1	XP_016871305.1	15 - 16	1553		97
GenBank mRNA	BC146857.1	-	32 - 33	3285	9056785	97
	BX648342.1	-	4 - 5	1420		97
	D50857.1	-	32 - 33	3246		97

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1000009276.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DOCK1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

phagocytosis, engulfment
apoptotic process
cytoskeleton organization
signal transduction
integrin-mediated signaling pathway
small GTPase mediated signal transduction
blood coagulation
positive regulation of epithelial cell migration
cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
SH3 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	ENST00000280333.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	ENST00000623213.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	NM_001290223.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	NM_001380.4	Refseq
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	ENST00000280333.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	ENST00000623213.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	NM_001290223.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	NM_001380.4	Refseq
Affymetrix Human Clariom D Assay	PSR1000163612.hg.1	TC1000009276.hg.1	Clariom D TC