Hs01076155_m1

• Gene Symbol: DIS3
• Gene Name: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
• Gene Aliases: 2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p
• Chromosome Location: Chr.13: 72755402 - 72782128 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DIS3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001322349.1	NP_001309278.1	3 - 4	743		114
	NM_014953.4	NP_055768.3	2 - 3	675		114
GenBank mRNA	AB001743.1	-	2 - 3	406		114
	AF330044.1	-	2 - 3	415		114
	AK314715.1	-	2 - 3	491		114
	AL832266.1	-	2 - 3	468		114
	BC038101.1	-	3 - 4	714	4827328	114
	BC056143.1	-	2 - 3	480	5505671	114

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC13000727.hg.1

Additional Information:

This assay is in the 5'UTR region of the BC038101.1,NM_001322349.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DIS3

Panther Classification:

Molecular Function -

exoribonuclease

Gene Ontology Categories:

Process(es)

rRNA processing
mRNA catabolic process
rRNA catabolic process
regulation of mRNA stability
positive regulation of GTPase activity
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
CUT catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic

Function(s)

3'-5'-exoribonuclease activity
RNA binding
endonuclease activity
guanyl-nucleotide exchange factor activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR13008389.hg.1	ENST00000377767.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008389.hg.1	ENST00000475871.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008389.hg.1	ENST00000545453.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008389.hg.1	NM_014953.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR13008389.hg.1	TC13000727.hg.1	HTA TC