Hs01872448_s1

• Gene Symbol: TLR2
• Gene Name: toll like receptor 2
• Gene Aliases: CD282, TIL4
• Chromosome Location: Chr.4: 153684080 - 153710643 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TLR2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001318787.1	NP_001305716.1	4	2879		116
	NM_001318789.1	NP_001305718.1	3	2669		116
	NM_001318790.1	NP_001305719.1	3	2646		116
	NM_001318791.1	NP_001305720.1	3	2635		116
	NM_001318793.1	NP_001305722.1	3	2631		116
	NM_001318795.1	NP_001305724.1	3	2610		116
	NM_001318796.1	NP_001305725.1	3	2595		116
	NM_003264.4	NP_003255.2	3	2654		116
	XM_011532215.2	XP_011530517.1	3	2579		116
	XM_011532216.2	XP_011530518.1	2	2526		116
	XM_017008573.1	XP_016864062.1	4	3125		116
	XM_017008574.1	XP_016864063.1	4	2807		116
	XM_017008575.1	XP_016864064.1	4	2851		116
	XM_017008576.1	XP_016864065.1	2	3425		116
GenBank mRNA	AF051152.1	-	2			118
	AI493140.1	-	1			116
	AK125659.1	-	1	3802		116
	BC033756.1	-	3	2548	5213439	116
	CB528396.1	-	1			116
	U88878.1	-	2	2527		116

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0400009048.hg.1
This assay targets the same location as HTA transcript cluster(s) TC04000775.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Human Chemokine Panel, Inventoried, Human_Chemokine, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TLR2

Gene Ontology Categories:

Process(es)

cytokine secretion involved in immune response
MyD88-dependent toll-like receptor signaling pathway
apoptotic process
inflammatory response
immune response
signal transduction
I-kappaB phosphorylation
positive regulation of gene expression
positive regulation of Wnt signaling pathway
lipopolysaccharide-mediated signaling pathway
interleukin-10 production
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor TLR1:TLR2 signaling pathway
toll-like receptor TLR6:TLR2 signaling pathway
positive regulation of NF-kappaB import into nucleus
detection of triacyl bacterial lipopeptide
detection of diacyl bacterial lipopeptide
innate immune response
positive regulation of transcription from RNA polymerase II promoter
regulation of cytokine secretion
positive regulation of inflammatory response
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
cellular response to diacyl bacterial lipopeptide
cellular response to triacyl bacterial lipopeptide

Function(s)

lipopolysaccharide binding
lipopolysaccharide receptor activity
receptor activity
transmembrane signaling receptor activity
protein binding
signaling pattern recognition receptor activity
Toll-like receptor binding
triacyl lipopeptide binding
peptidoglycan binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR04010699.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04010699.hg.1	TC04000775.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04010697.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04010697.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04010697.hg.1	TC04000775.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR04010698.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04010698.hg.1	NM_003264.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04010698.hg.1	TC04000775.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR0400162114.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162114.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162114.hg.1	TC0400009048.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	TC0400009048.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162113.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162113.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162113.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162113.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162113.hg.1	TC0400009048.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0400162112.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162112.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162112.hg.1	ENST00000260010.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400162112.hg.1	NM_003264.4	Refseq
Affymetrix Human Clariom D Assay	PSR0400162112.hg.1	TC0400009048.hg.1	Clariom D TC