Hs04330281_s1

• Gene Symbol: NODAL
• Gene Name: nodal growth differentiation factor
• Gene Aliases: HTX5
• Chromosome Location: Chr.10: 70431936 - 70441709 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NODAL
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_018055.4	NP_060525.3	2	834		89
GenBank mRNA	BC033585.1	-	2	728		89
	BC104976.1	-	2	834	8143979	89
	BC112025.1	-	2	846	8327493	89

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Inventoried, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene NODAL

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
trophectodermal cellular morphogenesis
neural fold formation
liver development
placenta development
embryonic placenta development
maternal placenta development
vasculature development
heart looping
inhibition of neuroepithelial cell differentiation
brain development
embryonic pattern specification
polarity specification of proximal/distal axis
regulation of gastrulation
positive regulation of vascular endothelial growth factor production
negative regulation of cell development
positive regulation of pathway-restricted SMAD protein phosphorylation
stem cell population maintenance
positive regulation of cell-cell adhesion
BMP signaling pathway
positive regulation of activin receptor signaling pathway
floor plate morphogenesis
endodermal cell differentiation
cell migration involved in gastrulation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
axial mesodermal cell fate specification
mesendoderm development
digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
formation of anatomical boundary
positive regulation of epithelial cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
embryonic process involved in female pregnancy
maternal process involved in parturition
positive regulation of SMAD protein import into nucleus
SMAD protein signal transduction
left lung morphogenesis
negative regulation of androgen receptor signaling pathway
epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
positive regulation of ERK1 and ERK2 cascade
transforming growth factor beta receptor signaling pathway involved in primitive streak formation
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of trophoblast cell migration
negative regulation of chorionic trophoblast cell proliferation
regulation of stem cell population maintenance

Function(s)

cytokine activity
transforming growth factor beta receptor binding
growth factor activity
morphogen activity
receptor agonist activity
type I activin receptor binding