Hs05043237_s1

• Gene Symbol: HTR2B
• Gene Name: 5-hydroxytryptamine receptor 2B
• Gene Aliases: 5-HT(2B), 5-HT-2B, 5-HT2B
• Chromosome Location: Chr.2: 231108230 - 231125778 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: HTR2B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000867.4	NP_000858.3	2	462		100
GenBank mRNA	AK313741.1	-	2	394		100
	BC063123.1	-	2	466	30321290	100

More Information

Additional Information:

This assay is in the 5'UTR region of the AK313741.1, BC063123.1, NM_000867.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, G-protein coupled receptor, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene HTR2B

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

neural crest cell migration
positive regulation of cytokine production
positive regulation of endothelial cell proliferation
G-protein coupled receptor internalization
heart morphogenesis
cardiac muscle hypertrophy
cGMP biosynthetic process
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
protein kinase C-activating G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
behavior
positive regulation of cell proliferation
negative regulation of autophagy
positive regulation of phosphatidylinositol biosynthetic process
neural crest cell differentiation
phosphatidylinositol 3-kinase signaling
intestine smooth muscle contraction
phosphorylation
calcium-mediated signaling
hepatic stellate cell activation
vasoconstriction
response to drug
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
positive regulation of GTPase activity
inositol phosphate metabolic process
embryonic morphogenesis
positive regulation of cytokine secretion
regulation of behavior
positive regulation of nitric-oxide synthase activity
release of sequestered calcium ion into cytosol
positive regulation of cell division
negative regulation of cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
protein kinase C signaling
cellular response to amine stimulus
cellular response to temperature stimulus
cellular response to serotonin

Function(s)

G-protein alpha-subunit binding
G-protein coupled serotonin receptor activity
GTPase activator activity
drug binding
serotonin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	ENST00000258400.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200016006.hg.1	NM_000867.4	Refseq