Mm00440491_g1

• Gene Symbol: Nos2
• Gene Name: nitric oxide synthase 2, inducible
• Gene Aliases: NOS-II, Nos-2, Nos2a, i-NOS, iNOS
• Chromosome Location: Chr.11: 78920859 - 78960232 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nos2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010927.3	NP_035057.1	10 - 11	1348		57
GenBank mRNA	AF065919.1	-	10 - 11	1345		57
	AF065920.1	-	10 - 11	1345		57
	AF065921.2	-	10 - 11	1345		57
	AF065922.2	-	9 - 10	1218		57
	AF065923.2	-	9 - 10	1218		57
	AY090567.1	-	9 - 10	1168		57
	BC062378.1	-	10 - 11	1357	4978648	57
	M84373.1	-	10 - 11	1349		57
	M87039.1	-	10 - 11	1420		57
	M92649.1	-	10 - 11	1356		57
	U43428.1	-	10 - 11	1236		57

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001171.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nos2

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

ovulation from ovarian follicle
response to hypoxia
arginine catabolic process
superoxide metabolic process
nitric oxide biosynthetic process
inflammatory response
nitric oxide mediated signal transduction
negative regulation of gene expression
peptidyl-cysteine S-nitrosylation
positive regulation of guanylate cyclase activity
response to lipopolysaccharide
cellular response to drug
regulation of cell proliferation
negative regulation of protein catabolic process
defense response to bacterium
negative regulation of blood pressure
regulation of protein kinase activity
positive regulation of vasodilation
regulation of insulin secretion
positive regulation of killing of cells of other organism
oxidation-reduction process
cellular response to lipopolysaccharide
cellular response to interferon-gamma

Function(s)

actin binding
NADPH-hemoprotein reductase activity
nitric-oxide synthase activity
receptor binding
iron ion binding
protein binding
calmodulin binding
beta-catenin binding
cAMP-dependent protein kinase regulator activity
FMN binding
oxidoreductase activity
protein kinase binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
cadherin binding
metal ion binding
flavin adenine dinucleotide binding
nitric-oxide synthase binding
Hsp90 protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100010924.mm.1	NM_010927.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100010924.mm.1	TC1100001171.mm.1	MTA TC