Mm00440674_m1

• Gene Symbol: Pdgfb
• Gene Name: platelet derived growth factor, B polypeptide
• Gene Aliases: PDGF-B, Sis
• Chromosome Location: Chr.15: 79995865 - 80014808 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pdgfb
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011057.3	NP_035187.2	1 - 2	871		80
GenBank mRNA	AF162784.1	-	1 - 2	61		80
	AK087840.1	-	1 - 2	1046		80
	BC053430.1	-	1 - 2	871	6330609	80
	BC064056.1	-	1 - 2	538	1380782	80

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1500001891.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pdgfb

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

embryonic placenta development
positive regulation of endothelial cell proliferation
monocyte chemotaxis
positive regulation of glomerular filtration
protein phosphorylation
substrate-dependent cell migration
multicellular organism development
synapse assembly
heart development
positive regulation of cell proliferation
response to wounding
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
neuron remodeling
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
glial cell development
cell projection assembly
actin cytoskeleton organization
positive regulation of cell migration
negative regulation of cell migration
positive regulation of protein autophosphorylation
negative regulation of protein binding
activation of protein kinase activity
activation of protein kinase B activity
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
paracrine signaling
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
eye photoreceptor cell development
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of blood vessel endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of DNA replication
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of mitotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of vasoconstriction
negative regulation of vasodilation
positive regulation of mitotic cell cycle, embryonic
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
regulation of peptidyl-tyrosine phosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of chemotaxis
positive regulation of cell division
retina development in camera-type eye
cell chemotaxis
branching involved in salivary gland morphogenesis
epithelial cell proliferation involved in salivary gland morphogenesis
cardiac vascular smooth muscle cell differentiation
positive regulation of protein tyrosine kinase activity
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
cellular response to growth factor stimulus
cellular response to mycophenolic acid
positive regulation of glomerular mesangial cell proliferation
metanephric glomerular mesangial cell development
metanephric glomerular mesangial cell proliferation involved in metanephros development
reactive oxygen species metabolic process
positive regulation of calcium ion import
positive regulation of hyaluronan biosynthetic process
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process
positive regulation of metanephric mesenchymal cell migration

Function(s)

receptor binding
platelet-derived growth factor receptor binding
collagen binding
growth factor activity
superoxide-generating NADPH oxidase activator activity
chemoattractant activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
platelet-derived growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1500014924.mm.1	NM_011057.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014924.mm.1	NM_011057.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014924.mm.1	TC1500001891.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500014922.mm.1	NM_011057.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014922.mm.1	NM_011057.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014922.mm.1	TC1500001891.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1500014923.mm.1	NM_011057.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014923.mm.1	NM_011057.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1500014923.mm.1	TC1500001891.mm.1	MTA TC