Mm00445695_m1

• Gene Symbol: Map2k2
• Gene Name: mitogen-activated protein kinase kinase 2
• Gene Aliases: AA589381, MEK2, MK2, Prkmk2
• Chromosome Location: Chr.10: 81105912 - 81124697 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map2k2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_023138.4	NP_075627.2	8 - 9	1191		56
GenBank mRNA	AK009392.1	-	8 - 9	1208		56
	AK011247.1	-	8 - 9	1185		56
	AK080574.1	-	8 - 9	1192		56
	AK171584.1	-	8 - 9	1180		56
	AK172055.1	-	8 - 9	1189		56
	AK181352.1	-	1 - 2	98		56
	AK186012.1	-	1 - 2	48		56
	AK208021.1	-	1 - 2	48		56
	AK217783.1	-	1 - 2	48		56
	BC014830.1	-	8 - 9	1170	4483473	56
	S68267.1	-	8 - 9	1112		56

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1000000881.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map2k2

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
regulation of protein phosphorylation
protein phosphorylation
phosphorylation
regulation of stress-activated MAPK cascade
peptidyl-serine autophosphorylation
regulation of axon regeneration
positive regulation of axonogenesis
lung morphogenesis
trachea formation
epithelial cell proliferation involved in lung morphogenesis
ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity
regulation of Golgi inheritance
positive regulation of cell motility
regulation of early endosome to late endosome transport

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
PDZ domain binding
protein complex scaffold
protein serine/threonine kinase activator activity
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1000006815.mm.1	NM_023138.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1000006815.mm.1	TC1000000881.mm.1	MTA TC