Mm01181031_m1

• Gene Symbol: Kdm1a
• Gene Name: lysine (K)-specific demethylase 1A
• Gene Aliases: 1810043O07Rik, AA408884, Aof2, D4Ertd478e, Kdm1, Lsd1, mKIAA0601
• Chromosome Location: Chr.4: 136550533 - 136602789 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Kdm1a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_133872.2	NP_598633.2	16 - 17	2241		84
GenBank mRNA	AK129170.1	-	16 - 17	2181		84
	BC019417.1	-	2 - 3	187		84
	BC059885.1	-	16 - 17	2228	6815975	84

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400003785.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Kdm1a

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein demethylation
multicellular organism development
cell proliferation
regulation of primitive erythrocyte differentiation
positive regulation of neuron projection development
chromatin modification
pituitary gland development
granulocyte differentiation
negative regulation of protein binding
histone H3-K9 demethylation
histone H3-K4 demethylation
positive regulation of chromatin binding
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of erythrocyte differentiation
positive regulation of megakaryocyte differentiation
positive regulation of cell size
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
guanine metabolic process
positive regulation of hormone biosynthetic process
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
muscle cell development
oxidation-reduction process
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of transcription from RNA polymerase II promoter by histone modification
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation

Function(s)

RNA polymerase II transcription factor binding
p53 binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
N-ethylmaleimide reductase activity
oxidoreductase activity
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
demethylase activity
histone demethylase activity
histone demethylase activity (H3-K4 specific)
histone demethylase activity (H3-K9 specific)
histone demethylase activity (H3-dimethyl-K4 specific)
MRF binding
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
transcription regulatory region DNA binding
flavin adenine dinucleotide binding
androgen receptor binding
epoxyqueuosine reductase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400031204.mm.1	NM_133872.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400031204.mm.1	NM_133872.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0400031204.mm.1	TC0400003785.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400031205.mm.1	NM_133872.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400031205.mm.1	NM_133872.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0400031205.mm.1	TC0400003785.mm.1	MTA TC