Mm01265781_g1

• Gene Symbol: Axin2
• Gene Name: axin2
• Gene Aliases: Axi1, Axil, Conductin
• Chromosome Location: Chr.11: 108917828 - 108950783 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Axin2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_015732.4	NP_056547.3	5 - 6	1549		74
GenBank mRNA	AF073788.1	-	5 - 6	1414		74
	AF205889.1	-	4 - 5	1254		74
	AK049192.1	-	5 - 6	1493		74
	AK142333.1	-	5 - 6	1551		74
	BC057338.1	-	5 - 6	1532	6827741	74

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001820.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Axin2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

somitogenesis
positive regulation of protein phosphorylation
intramembranous ossification
secondary heart field specification
chondrocyte differentiation involved in endochondral bone morphogenesis
regulation of transcription, DNA-templated
cell death
cell proliferation
negative regulation of cell proliferation
dorsal/ventral axis specification
positive regulation of epithelial to mesenchymal transition
positive regulation of cell death
Wnt signaling pathway
regulation of Wnt signaling pathway
bone mineralization
regulation of mismatch repair
cellular protein localization
regulation of catenin import into nucleus
negative regulation of catenin import into nucleus
termination of G-protein coupled receptor signaling pathway
odontogenesis
positive regulation of GTPase activity
maintenance of DNA repeat elements
negative regulation of osteoblast differentiation
positive regulation of protein kinase activity
mRNA stabilization
regulation of chondrocyte development
regulation of centromeric sister chromatid cohesion
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Function(s)

GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
ubiquitin protein ligase binding
armadillo repeat domain binding
I-SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100017167.mm.1	NM_015732.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100017167.mm.1	NM_015732.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100017167.mm.1	TC1100001820.mm.1	MTA TC